Antibiotics Flashcards
penicillin/ampicillin mech of action:
enter the bacteria via the cell wall, inside the cell they bind to penicillin-binding protein, bacteria cells die from cell lysis, penicillin does not kill other cells in the body
penicillin/ampicillin indications:
prevents and treats infections caused by susceptible bacteria
-gr5am-positive bacteria
-strep/staph
-limited bactericidal action against gram-negative bacteria
penicillin/ampicillin classification:
penicillin/antibiotics
penicillin/ampicillin adv effects;
allergy, pruritus,
Doxycycline classification:
tetracycline
Doxycycline mech of action:
inhibits bacterial growth/stops essential functions
What does Doxycycline treat?
rickettsial infections such as rocky mountain fever, chlamydia, mycoplasma, gram negative organisms
What reduces absorption of tetracyclines?
dairy products, antacids, iron salts
Doxycycline adv effects:
discoloration in teeth, should avoid w pregnancy, PHOTOSENSITVITY, alterations in vaginal flora, GI upset
Erythromycin/Azithromycin classification:
Macrolides
Erythromycin/Azithromycin mech of action:
inhibit bacterial protein synthesis by reversibly binding to the 50S ribosomal subunit, specifically the 23S rRNA, thus preventing translation of mRNA
Erythromycin/Azithromycin indications:
strep, respiratory infections, syphilis, lyme disease, STDS
Erythromycin/Azithromycin adv effects:
GI effects, primarily with erythromycin
-N/V, liver issues, jaundice
vancomycin:
-should be infused over 60 minutes, monitor IV closely
-REDMAN SYNDROME
-antihistamine will be taken to reduce adv effects
-ensure hydration so pt doesn’t have kidney issues
vancomycin cont.:
-FOR MRSA (other gram-positive)
-ototoxicity/nephrotoxicity main adv effects
