Hexose Mono-phosphate Pathway Flashcards
1
Q
which reaction in the hexose monophosphate pathway generates NADPH
A
glucose 6-phosphate to ribulose 5-phosphate
it would generate 2 NADPH
2
Q
NADPH is the principal redox intermediate in _____
A
anabolic processes (fatty acid synthesis, cholesterol synthesis, nucleotide synthesis)
3
Q
what enzyme does NADPH work with to protect cells against free radicals
A
glutathione reductase in order to regenerate gluatathione
4
Q
the HMP is the sole source of NADPH in
A
the red blood cell
5
Q
deficiency in glucose 6-phosphate dehydrogenase leads to ___
A
hemolytic anemia when red blood cells are oxidatively challenged