Hexose Mono-phosphate Pathway Flashcards

1
Q

which reaction in the hexose monophosphate pathway generates NADPH

A

glucose 6-phosphate to ribulose 5-phosphate

it would generate 2 NADPH

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2
Q

NADPH is the principal redox intermediate in _____

A

anabolic processes (fatty acid synthesis, cholesterol synthesis, nucleotide synthesis)

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3
Q

what enzyme does NADPH work with to protect cells against free radicals

A

glutathione reductase in order to regenerate gluatathione

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4
Q

the HMP is the sole source of NADPH in

A

the red blood cell

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5
Q

deficiency in glucose 6-phosphate dehydrogenase leads to ___

A

hemolytic anemia when red blood cells are oxidatively challenged

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