Diabetes

Question 1

T or F: most tissues are able to detect presence of glucose in the blood

Answer 1

F. the pancreas beta cells are able to detect, but most tissues only measure/detect insulin

Question 2

Type 1 Diabetes is an autoimmune disease where the B cells of the pancreas are destroyed. What is a major consequence of this?

Answer 2

-destruction of beta cells of pancreas results on inability of body to synthesize and secrete insulin

Question 3

what happens when there is no insulin?

Answer 3

• glucagon is de-repressed which indicates to the liver that we are in a fasting mode (even if we just ate)
• liver, muscle, and adipose cells lose the insulin instructions on what to do

Question 4

what are the 3 P’s of Type 1 diabetes?

Answer 4

• polydipsia
• polyphagia
• polyuria

Question 5

which blood marker is a good test for learning patient adherence to managing blood sugar levels?

Answer 5

-HbA1C:

glycated Hb

Question 6

what is the underlying mechanism for Type 2 diabetes?

Answer 6

-insulin resistance is developed which results in inability of target organs to respond to insulun

Question 7

what glucose transporter is sensitive to insulin?

Answer 7

GluT-4