HERPES ZOSTER Flashcards

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1
Q

Etiologi Herpes Zoster?

A

Varicella Zoster Virus (VZV)

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2
Q

Patogenesis Herpes Zoster?

A
  • Infeksi dari konjungtiva dan mukosa saluran pernapasan akut
  • Replikasi viral di lymph node
  • Primary infection
  • Sebagian VZV pergi ke ganglion radiks dorsalis dan jadi dorman
  • Saat imun lemah dia reaktivasi
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3
Q

Ada berapa fase Herpes Zoster? sebutkan ciri - cirinya

A

Fase prodormal: 1-3 hari
–> Gangguan sensasi dermatomal : parestesia & nyeri tajam seperti disayat

Fase ruam:
- Ruam:
makulo - papul - vesikel - pustule - krusta
- Dermatomal dan unilateral.
- Predileksi –> Level T3 - L2

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4
Q

Diagnosis Herpes Zoster?

A

Diagnosis secara klinis
Pemeriksaan penunjang :
- Tzanck Test –> sel datia berinti banyak (non-spesifik)
- PCR –> DNA VZV positif (gold standard)

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5
Q

Pengobatan Herpes Zoster ?

A

Terapi Simtomatis
Terapi Antivirus
1) Asiklovir 5 x 800 mg selama 7 - 10 hari
–> Anak < 12 tahun 30 mg/kgBB
–> Anak >12 tahun 60 mg/kgBB
2) Valasiklovir 3 x 1000 mg
3) Famsiklovir 3 x 250 mg
SELAMA 7 HARI

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