Herpes Virus ( Varicella Zoster)

Question 1

What does Varicella zoster cause?

Answer 1

Chicken pox

Question 2

Infectivity is maximum at what stage?

Answer 2

Initial stage when the virus is abundant in the URT

Question 3

Entry of VZV?

Answer 3

Respiratory tract

Conjunctivita

Question 4

Incubation period of VZV?

Answer 4

1-2weeks

Question 5

Baccalaureate lesion appear when?

Answer 5

Early stage

Question 6

The patient having chicken pox is considered to be infectious when?

Answer 6

2 days before onset of lesion and 5 day after

Question 7

Little prodromal illness with fever occurs in?

Answer 7

Children

Question 8

The rash appears on what region of the body?

Answer 8

Trunks

Question 9

Evolution of rash?

Answer 9

Macule

Papule ( day 2)

Vesicle (day 4)

Pustle $ scab (crust) (day 6)

Question 10

What is chicken pox?

Answer 10

Chicken pox is a highly contagious viral disease caused by varicella zoster virus which is characterized by hundreds of itchy, fluid filled blisters on the body that bursts and form crusts.

Question 11

Does bullous lesion occur occasionally in VZV, yes or no?

Answer 11

Yes

Question 12

Other complications of VZV?

Answer 12

Myocarditis

Nephritis

Acute cerebellum ataxia

Meningitis

Encephalitis may show

Question 13

Chicken pox in pregnancy can be dangerous for both?

Answer 13

Mother( more severe in pregnant women) and baby

Question 14

Baby may develop complications depending on?

Answer 14

Period of gestation

Question 15

Infants may develop?

Answer 15

Fetal varicella syndrome

Cicatrising skin lesion

Hypoplasia of limbs

Chorioretinitis

CNS defects

Question 16

Lab diagnosis of VZV

Answer 16

Multinucleated gaint cells

Type A intranuclear inclusion bodies

Question 17

Treatment of chicken pox?

Answer 17

Varicella vaccine

Modified lyophilized form of vaccine for children 1-12

Passive protection- varicella zoster immunoglobulin

ACYCLOVIR and FAMICICLOVIR are effective ( drug of choice)