Herpes and Cytomegalovirus

Question 1

Herpes prototype

Answer 1

Acyclovir

Question 2

Acyclovir indications

Answer 2

Treatement of HSV 1 and 2; treatment of severe genital HSV infections; treatement of HSV encephalitis; acute treatment of shingle and chickenpox; ointment for the treatment of genital herpes infections; cream for the treatment of cold sores (herpes labialis).

Question 3

Acyclovir actions

Answer 3

Inhibits viral DNA replication

Question 4

Acyclovir route, onset, peak, duration

Answer 4

Oral, varies, 1.5 - 2 h, not known;
IV, immediate, 1 h, 8 h;
Topical, not generally absorbed systemically

Question 5

Acyclovir adverse effects

Answer 5

Headache, vertigo, tremors, nausea, vomiting, rash.