Fusion Inhibitor Flashcards

1
Q

Fusion Inhibitor

A

Enfuvirtide (For use in adults and children > 6 years old).

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2
Q

Enfuvirtide indications

A

Treatment of HIV-1-infected patients who have experienced clinical or immunological deterioration after treatment with other agents, in combination with other antiretrovirals.

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3
Q

Enfuvirtide actions

A

Prevents the entry of the HIV-1 virus into cells by inhibiting the fusion of the virus membrane with the cellular membrane.

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4
Q

Enfuvirtide route, onset, peak

A

Subcutaneous, slow, 4-8 h

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5
Q

Enfuvirtide adverse effects

A

Headache, nausea, vomiting, diarrhea, rash, anorexia, pneumonia, chills, injection-site reactions.

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