Fusion Inhibitor Flashcards
1
Q
Fusion Inhibitor
A
Enfuvirtide (For use in adults and children > 6 years old).
2
Q
Enfuvirtide indications
A
Treatment of HIV-1-infected patients who have experienced clinical or immunological deterioration after treatment with other agents, in combination with other antiretrovirals.
3
Q
Enfuvirtide actions
A
Prevents the entry of the HIV-1 virus into cells by inhibiting the fusion of the virus membrane with the cellular membrane.
4
Q
Enfuvirtide route, onset, peak
A
Subcutaneous, slow, 4-8 h
5
Q
Enfuvirtide adverse effects
A
Headache, nausea, vomiting, diarrhea, rash, anorexia, pneumonia, chills, injection-site reactions.