Hepatologia 2 - Cirrose e suas causas DOENÇA DE WILSON Flashcards

1
Q

Diagnostico Dça de Wilson

A

Diminuiçao da ceruloplasmina
Aumento do cobre urinario 24h
Bx hepatica

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2
Q

Etiologia Dça de Wilson

A

Dça autossomica recessiva - mutaçao ATP7B

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3
Q

Quadro clinico da Doença de Wilson

A

FÍGADO E CÉREBRO

Fígado: hepatite cronica, cirrose, hepatite aguda por hemolise
Cérebro: sindrome parkinsoniana, dist psiquiatricos

(fases tardias: rim, ossos, coraçao, glandulas)

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4
Q

TTO de dça de Wilson

A

Sais de zinco
Sais de zinco + Trientine (d hepatica Descompensada)
Sais de Zinco + Tetratiomolibdato (neuropq)

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