Hepatobiliary Disease Review Flashcards
Most common benign liver tumor?
- Hemangioma
Clinical features of liver hemangioma?
- more common in women (3:1 ratio)
- most are asymptomatic
- stable with low risk of rupture
- 0 reports of malignant degeneration
- resection should be considered if mass effect is causing symptoms
What kind of liver tumor should be on your differential if patient is on hormonal therapy? (e.g OCPs, steroids)
- hepatic adenoma
CT scan characteristics of hepatic angioma?
- Arterial phase, portal venous phase, delayed phase
- Arterial: peripheral nodular enhancement (non-homogenous)
- portal venous: centripetal filling
- delayed: enhancement of entire mass
CT scan characteristics of hepatic adenoma?
- Arterial phase, portal venous phase, delayed phase
- Arterial: peripheral then leading to centripetal enhancement (homogenous)
- portal venous: isodense or hypodense (compared to surrounding parenchyma)
- delayed: isodense or hypodense
CT scan characteristics of Focal Nodular Hyperplasia?
- Arterial phase, portal venous phase, delayed phase
- arterial: intense enhancement, central fibrous scar with radiating septa
- venous phase: partial filling
- delayed: enhancement of central scar
First step of a right hepatectomy
- cholecystectomy
most common sign of recurrence for gall bladder cancer?
- ascites
- jaundice
What is the underlying physiology behind hepatorenal syndrome?
- liver failure leads to severe vasodilation and arterial hypovolemia -> kidneys see decreased BP and therefore retain sodium/water
Pharmacological therapy for HRS?
- Albumin + vasoconstrictive agent (most common is terlipressin)
Patient is post op from a VARD, has small volume hematemesis…next step?
- CTA of the abdomen and possible angio-embolization
- this is potentially a herald bleed from a pseudoaneurysm
what are primary bile salts conjugated with in hepatocytes?
- taurine and glycine
where is the bulk of conjugated bile acids absorbed in the GI tract?
- 80% of all secreted conjugated bile salts are absorbed in the terminal ileum
what vitamins do bile acids help absorb?
- fat soluble ones
- A D E K
indication to resect a hepatic adenoma
- male gender
- size > 5cm
- symptomatic
- suspicion of malignancy on imaging
jaundice, right upper quadrant pain, hematemesis…what do you call this triad (not an eponym)
hemobilia
Male who recently traveled to the tropics has a fever and right upper quadrant pain. CT scan shows a large cystic mass with a thick hyperenhancing wall…what does he have?
Entamoeba histolytica infection
Male who recently traveled to the tropics has a fever and right upper quadrant pain. CT scan shows a large cystic mass with a thick hyperenhancing wall…how do you treat it?
10 days of metronidazole
E. Histolytica infection
when do you consider a TIPS procedure for ascites?
when 2-3 large volume paracentesis are required per month despite salt restriction and maximized diuretic use
In children, what is the most common cause of portal vein thrombosis
previously infected umbilical vein
- be on the look out for ICU babies
mass in liver that is hypointense on T1 but hyperintense on T2 MRI imaging?
likely a hepatic hemangioma