Colorectal Review Flashcards
How do you perform an extended left hemicolectomy?
Colonic resection between the left third of the transverse colon and the colorectal junction. The inferior mesenteric vessel and the left middle colic vessel are ligated at their origin in combination with a regional lymphadenectomy.
What features of a colonic polyp biopsy would necessitate oncologic resection?
- poor differentiation
- vascular or lymphatic invasion
- invasion below the submucosa
- positive resection margin
- cancer within 2mm of resection margin
- involvement at the base of the polyp
- incomplete resection of polyp
Which Haggitt Classification necessitates oncologic resection?
level 4 - invading the submucosa, below the stalk of the polyp
Surveillance recommendation for the follow:
- normal colonoscopy
- <20 hyperplastic polyps < 1cm
Routine colonoscopy in 10 years, this is a normal colonoscopy
Surveillance recommendation for the follow:
- 3-4 adenomas < 1cm in size
- 1 Hyperplastic polyp > 1cm in size
Follow up colonoscopy in 3-5 years
- unlikely to be tested given the gray area of recommendation
Surveillance recommendation for following:
- 5-10 adenomas found on colonoscopy
Follow up colonoscopy in 3 years
Surveillance recommendation for following:
- Sessile polyp > 1cm
follow up colonoscopy in 3 years
Surveillance recommendation for following:
- Polyp with tubulovillous/villous features
follow up colonoscopy in 3 years
Surveillance recommendation for following:
- polyp with high grade dysplasia
follow up colonoscopy in 3 years
Surveillance recommendation for following:
- > 10 adenomas found on colonoscopy
repeat colonoscopy in 1 year
Surveillance recommendation for following:
- adenoma removed piecemeal on colonoscopy
repeat colonoscopy in 3-6 months
treatment for pseudomyxoma peritonitis
- Cytoreductive surgery
- Hyperthermic intraperitoneal chemotherapy
What is cytoreductive surgery?
- for treatment of PMP it is defined as having no gross disease greater than 2mm in size
Preferred treatment for anal squamous cell carcinoma
- radiation and chemotherapy upfront
- salvage APR for recurrences
Preferred treatment for anal melanoma
- wide local excision
Preferred treatment for anal adenocarcinoma
- APR followed by adjuvant chemotherapy
most common small bowel malignancy
- metastatic lesion
small bowel tumor found to be a metastatic lesion…most likely source is?
melanoma
Patient with chronic lower right quadrant pain, presumed appendicitis. In OR normal appendix with inflamed cecum and/or terminal ileum…what do you do?
- take out appendix even if grossly normal
- patient likely has Chron’s and is presenting with terminal ileitis
Peutz-Jeghers syndrome is characterized by what
- hamartomatous polyps throughout GI
- hyperpigmented macules on the buccal mucosa, lips, and digits
Peutz-Jeghers increases the risk of what?
- GI malignancy
- extraintestinal malignancy (breast, uterus, cervix, testes, pancreas, lung)
How do you diagnose Chronic Appendicitis
its a diagnosis of exclusion, must rule out everything else
patient with protocolectomy with J-pouch anastomosis, presenting with pouchitis…what is the treatment?
- Antibiotic treatment with metronidazole or a fluoroquinolone
- 5-ASA can be used for refractory cases
how do you close a previous ostomy site?
purse string closure…has lowest complication rate of any closure method
What does Toxin A from Clostridium Difficile result in?
Intestinal necrosis
How much invasion in a T1 colorectal adenocarcinoma lesion?
to but not through the muscularis mucosa
How much invasion in a T2 colorectal adenocarcinoma lesion?
invades into muscularis propria
How much invasion in a T3 colorectal adenocarcinoma lesion?
invades through the muscularis propria into pericolorectal tissue
How much invasion in a T4 colorectal adenocarcinoma lesion?
invades through visceral peritoneum or into adjacent organs
N1 disease = how many + LNs
1-3
Patient has stage III rectal cancer after neoadjuvant therapy and surgery…what is next step
adjuvant chemo
- this only pertains to stage III rectal cancer
when do you do recommend surgical intervention for an anal fissure?
after patient has tried stool softeners, laxatives, situ baths, and calcium channel blocker ointment like nifidepine
describe the delorme procedure
for rectal prolapse, incision in mucosa of prolapsed rectum is made 1 cm above dentate line. You take out the mucosa of all the redundant rectum and then plicate muscularis propria and bring mucosa edges together
How is the altemeier procedure different than the delorme?
used for rectal prolapse greater than 5 cm, full thickness excision is made instead of just a mucosal excision
1.7 cm adenocarcinoma at tip of appendix on final pathology of appendicitis, next step
Right hemicolectomy
1.7 cm appendiceal carcinoma at tip of appendix on final pathology of appendectomy, next step
no further steps necessary
patient had a left hemicolectomy, on follow up reports inability to ejaculate
injury to superior hypogastric plexus, occurs with high ligation of inferior mesenteric artery
what kind of nerve fibers constitute the superior hypogastric plexus
sympathetic nerves
what kinds of nerves constitute the inferior hypogastric plexus
parasympathetic and sympathetic nerve fibers
at what size should you drain an intra-abdominal abscess?
if its greater than 3 cm, any smaller should be treated with antibiotics
purpose of anal electromyography
- evaluate patients thought to be neurogenic sphincter weakness
use of defecography
detect enteroceles, rectoceles, and rectal prolapse
use of endoanal US
detect sphincter dysfunction in patients with fecal incontinence
standard treatment for a low rectovaginal fistula
endorectal advancement flap
best way to diagnose a fistula from diverticulitis?
CT scan of the abdomen and pelvis
- will show air in the bladder
most common cause of lower GI bleeds in older patients?
diverticulosis
most common symptom of an abdominal carcinoid tumor
abdominal pain
secondary causes of constipation
- drugs
- neurogenic
- non-neurogenic
- irritable bowel syndrome
how do you diagnose slow transit time constipation
- use radio-opaque markers, if there are more than 5 markers on day six you have a positive test
surgery for an upper rectum cancer?
left hemicolectomy
how far away from the anal verge is an upper rectum cancer?
10-12 cm above the anal verge
how far away is a middle rectal cancer from the anal verge?
7-10 cm from the anal verge
surgery indicated for a middle rectal cancer?
low anterior resection
surgery indicated for a lower rectal cancer
total abdominal perineal resection
when can you do a transanal excision of a rectal cancer?
a T1 rectal cancer with the following:
- within 8 cm of anal verge
- < 3cm in size / < 30% circumference
- freely mobile
what is unique about the Lugano staging system for non-hodgkin lymphoma?
there is no Stage III
most common cause of severe GI bleeding?
- Diverticulosis
Infliximab
- monoclonal Ig-G1 antibody with affinity to TNFa
patient with Crohn’s disease, what is the indication(s) for Infliximab?
- perianal fistula disease
- Crohn’s disease refractory to medication
management of < 1cm rectal carcinoid tumor
endoscopic or local excision
management of 1-2 cm rectal carcinoid tumor
- full thickness excision
- if invades muscularis or LN involvement need full surgical resection (APR) with total mesolectal excision
management of > 2cm rectal carcinoid tumor?
full surgical excision (APR)
when would you need a hemicolectomy if pathology showed an appendices mucinous neoplasm
- > 2 cm in size
- postive margin
- lymphovascular invasion
- mesoappendiceal invasion
what mutation would prevent you from using Cetuximab for advance colorectal cancer
KRAS mutation
if you see an anal fissure laterally what should you be suspicious of
Chron's disease malignancy HIV Syphilis tuberculosis
if you see multiple anal fissures what should you be suspicious of
trauma
how many lymph nodes do you need to harvest for a colon cancer
12 minimum
When would you do pre-sacral drainage for a rectal injury repair
- if you repair it trans-abdominally
how long should you wait to repair a rectovaginal fistula
- 3-6 months, some will spontaneously repair