Hepatitis Things Cause I Don't Get It

Question 1

The presence of this antigen indicates that the patient is currently infected with Hepatitis B; its persistence for 6 months or longer indicates chronic infection. Earliest indicator of acute infection.

Answer 1

Hepatits B SURFACE antigen (HBsAg)

Question 2

Protein which is encoded by the Hepatitis B virus and is expressed when the virus is replicating at a high level. It is often found in patients who have abnormal LFTs and chronic Hepatitis. Its presence indicates high infectivity.

Answer 2

Hepatitis B ENVELOPE antigen

Question 3

If this is positive in a patient, it means that at some point in their life they have been exposed to Hepatitis B.

Answer 3

Hepatits B CORE antibody (HBcAb) There is no serologic test for the antigen. The only way to be positive for the core antibody is if you have been infected with the virus, since the vaccine does NOT include the Hep B core.

Question 4

When present, it sometimes indicates that the level of replication of the Hepatitis B virus is lower.. If this is present a person is most likely in the process of fighting off a recurrent Hep B infection.

Answer 4

Hepatitis B ENVELOPE antibody

Question 5

If produced in large amounts (>100 IU) it usually indicates that the patient has cleared the virus (if they have been infected) and are now immune. Could also indicate that the person was vaccinated and has immunity to Hep B.

Answer 5

HBsAb (Hepatitis B SURFACE antibody)

Question 6

Drug that specifically inhibits HBV DNA polymerase; SUPPRESSES HBV replication

Answer 6

Lamivudine (Epivir)

Question 7

You would check this level if you were assessing for an acute Hep A infection

Answer 7

Anti-hepatitis A virus IgM

Question 8

You would check this level if you were assessing for a chronic hep A infection

Answer 8

Anti-hepatitis A virus IgG

Question 9

How long will the hepatitis A IgM be positive for?

Answer 9

3-6 months

Question 10

How long will the hepatitis A IgG be positive for?

Answer 10

10 years

Question 11

With hepatitis A, what will the AST and ALT levels be?

Answer 11

May exceed levels of 1000 (8X elevated)

Question 12

How do you treat hepatitis A?

Answer 12

Self limiting - supportive

Question 13

What lab result would tell you that you need to treat the person with hepatitis B?

Answer 13

HBeAg - This is positive when the virus is replicating at a high level!!!

Question 14

What does fulminant hepatitis B result from?

Answer 14

Massive immune-mediated lysis of infected hepatocytes

Question 15

What is typically used for 6 months in the treatment of Hepatitis B and C

Answer 15

Peg-Interferon Alpha

Question 16

Which medication is for the eradication of genotype 1 HCV?

Answer 16

Harvoni for 12 weeks

Question 17

How do you treat genotype 2 HCV? (Chronic HCV)

Answer 17

Sofosbuvir and Ribavirin for 12 weeks

Question 18

What is the best prevention for Hepatitis C?

Answer 18

SCREEN!

Question 19

What strains of hepatitis are there vaccines for?

Answer 19

A and B