HEPATITIS

Question 1

What family and genus does Hepatitis A belong to?

Answer 1

Picornaviridae, Hepatovirus.

Question 2

What family and genus does Hepatitis B belong to?

Answer 2

Hepadnaviridae, Orthohepadnavirus.

Question 3

What family and genus does Hepatitis C belong to?

Answer 3

Flaviviridae, Hepacivirus.

Question 4

What family and genus does Hepatitis D belong to?

Answer 4

Delta virus, Deltaviridae.

Question 5

What family and genus does Hepatitis E belong to?

Answer 5

Hepeviridae, Hepevirus.

Question 6

What are the characteristics of Hepatitis A?

Answer 6

Unenveloped, icosahedral.

Question 7

What are the characteristics of Hepatitis B?

Answer 7

Enveloped, icosahedral.

Question 8

What are the characteristics of Hepatitis C?

Answer 8

Enveloped, icosahedral.

Question 9

What are the characteristics of Hepatitis D?

Answer 9

Enveloped, uncertain symmetry.

Question 10

What are the characteristics of Hepatitis E?

Answer 10

Unenveloped, icosahedral.

Question 11

What type of virus is Hepatitis A?

Answer 11

ssRNA.

Question 12

What type of virus is Hepatitis B?

Answer 12

dsDNA (incomplete).

Question 13

What type of virus is Hepatitis C?

Answer 13

ssRNA.

Question 14

What type of virus is Hepatitis D?

Answer 14

Circular defective ssRNA.

Question 15

What type of virus is Hepatitis E?

Answer 15

ssRNA.

Question 16

What is the route of transmission for Hepatitis A?

Answer 16

Feco-oral, anal intercourse.

Question 17

What is the route of transmission for Hepatitis B?

Answer 17

Sexual transmission, vertical, blood and blood products, parenteral.

Question 18

What is the route of transmission for Hepatitis C?

Answer 18

90–95% transfusion-related.

Question 19

What is the route of transmission for Hepatitis D?

Answer 19

Similar to HBV, not as much sexually transmitted.

Question 20

What is the route of transmission for Hepatitis E?

Answer 20

Feco-oral.

Question 21

Is Hepatitis A chronic?

Answer 21

Rarely/never chronic.

Question 22

Is Hepatitis B chronic?

Answer 22

Chronic, especially in infants (5–10% in adults).

Question 23

Is Hepatitis C chronic?

Answer 23

75–85% chronic (including 10–15% cirrhosis).

Question 24

Is Hepatitis D chronic?

Answer 24

10% in coinfection, 90% in superinfection.

Question 25

Is Hepatitis E chronic?

Answer 25

Rarely chronic.

Question 26

What is the incubation period of Hepatitis A?

Answer 26

3–5 weeks (mean 4 weeks).

Question 27

What is the incubation period of Hepatitis B?

Answer 27

Long (50–80 days), variable.

Question 28

What is the incubation period of Hepatitis C?

Answer 28

15–160 days (average 50 days).

Question 29

What is the incubation period of Hepatitis D?

Answer 29

Similar to HBV.

Question 30

What is the incubation period of Hepatitis E?

Answer 30

6–8 weeks.

Question 31

What diagnostic method is used for Hepatitis A?

Answer 31

Detection of serum IgM antibodies and HAV detection.

Question 32

What diagnostic method is used for Hepatitis B?

Answer 32

In blood: HBsAg, HBeAg, HBV DNA, or HBc antibody.

Question 33

What diagnostic method is used for Hepatitis C?

Answer 33

ELISA for antibodies and PCR for HCV RNA.

Question 34

What diagnostic method is used for Hepatitis D?

Answer 34

Serology for IgM and IgG, and RT-PCR for active infection.

Question 35

What diagnostic method is used for Hepatitis E?

Answer 35

PCR for HEV RNA and detection of HEV-specific IgM.