Hepatic Disorders Flashcards

1
Q

labs that will be increased if there is an issue with the liver

A
AST
ALT
protein
prothrombin time
ammonia
cholesterol
alkaline phosphate
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2
Q

watch for this following liver biopsy

A

bleeding

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3
Q

signs of bleeding following liver biopsy

A

bruising in abd area

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4
Q

most common cause of hepatic dysfunction

A

malnutrition related to alcoholism

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5
Q

besides alcoholism, causes of hepatic dysfunction

A
infection
anoxia
metabolic disorders
nutritional deficiencies
hypersensitivity states
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6
Q

manifestations of hepatic dysfunction

A
jaundice
portal htn
ascites
varices
hepatic encephalopathy
nutritional deficiencies
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7
Q

cause of hepatic encephalopathy/coma

A

increased ammonia levels

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8
Q

where do the varices associated with hepatic dysfunction occur

A

esophagus

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9
Q

obstructed blood flow thru the liver resulting in increased pressure throughout the portal venous system

A

portal HTN

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10
Q

what does portal HTN result in

A

ascites

esophageal varices

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11
Q

in a pt with ascites, is percussion of the abdomen heard as tympany or a dull sound

A

dull

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12
Q

T or F: the HOB should be flat in a pt with ascites

A

FALSE, should be elevated or pt may be sitting in chair

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13
Q

tx of ascites

A
low sodium diet
diuretics
bed rest
paracentesis
admin salt poor albumin
TIPS
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14
Q

life threatening complication of hepatic dysfunction

A

hepatic encephalopathy

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15
Q

fetor hepaticus

A

breath smells like stool

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16
Q

asterixis

A

an unusual hand movement indicative of increased ammonia levels

17
Q

med given to reduce serum ammonia levels

A

lactulose

18
Q

how does lactulose work

A

usually given PO, acts as a laxative

19
Q

given to pts with hepatic dysfunction to minimize protein catabolism

A

IV glucose

20
Q

ways to reduce ammonia in GI tract

A

suction
enemas
oral antibiotics

21
Q

manifestations of bleeding of esophageal varices

A

hematemesis
melena (black, tarry feces)
general deterioration
shock

22
Q

pts with cirrhosis should undergo screening ____ every 2 years

A

endoscopy

23
Q

meds given to decrease bleeding of esophageal varices

A

vasopressin
somatostatin
octretide

24
Q

what med may be used in conjuction with vasopressin when bleeding of esophageal varices is occurring

A

nitroglycerin—reduce CA vasoconstriction

25
Q

tx procedures for esophageal varices

A

balloon tamponade
endoscopic sclerotherapy
esophageal banding

26
Q

this procedure can damage the stomach lining so protonix should be given before performing it

A

endoscopic sclerotherapy

27
Q

blood breakdown in the GI tract when esophageal varices are bleeding can cause what

A

hepatic encephalopathy

28
Q

a systemic viral infection that causes necrosis and inflammation of liver cells with characteristic sxs and cellular/biochemical changes

A

viral hepatitis

29
Q

nonviral hepatitis is induced by what

A

toxic causes

drugs

30
Q

how is hep a transmitted

A

fecal-oral

31
Q

length of illness for hep a

A

4-8 weeks

32
Q

early manifestations of hep a

A

flu-like sxs
low-grade fever
anorexia

33
Q

how is hep b transmitted

A

through blood found in blood, saliva, semen, vaginal secretions
sexually transmitted
from mother to infant during birth

34
Q

manifestations of hep b

A

insidious and variable

similar to hep a

35
Q

best way to prevent hep b

A

vaccine

36
Q

meds for chronic hep b

A

alpha interferon

antivirals: Epivir and Hepsera

37
Q

how is hep c transmitted

A

through blood
sexually transmitted
needle sticks/sharing of needles

38
Q

the most common bloodborne infection

A

hep c

39
Q

antiviral agents used in hep c

A

interferon

ribavirin