Hemostasis

Question 1

Hemostasis can be achieved by:

Answer 1

– Clot formation or vessel spasm
– Mechanical pressure
– Ligation
– Hemostatic agents
– Thermally

Question 2

Hemostatic Process

Answer 2

. When a vessel is injured
– Vasoconstriction begins
. Platelets adhere to
vessel walls
. Platelets release
epinephrine, serotonin
& ADP (adenosine
diphosphate)–causes
more platelets to clump
. ADP causes more platelets to adhere
. Platelet aggregate forms
. Permanent thrombus forms after clotting factor reaction (Prothrombin –
thromboplastin = thrombin – fibrinogen = fibrin)

Question 3

Control of bleeding post
surgery

Answer 3

. 50% of post operative bleeding is from
poor hemostasis
. Key to proper hemostasis
– Gentle tissue handling
– Proper closure without dead space
– Proper wound dressing

Question 4

Hemophilia

Answer 4

Disorder in which your blood doesn’t clot
normally because it lacks sufficient blood-
clotting proteins (clotting factors).
– Most common
– Congenital
– Preoperative testing is useful

Question 5

Acquired Hemostatic Disorders

Answer 5

. Liver disease
. Anticoagulant therapy
. Aplastic anemia
. Alcoholic liver failure
. Drug-therapy-induced platelet dysfunctions
. No aspirin for one week prior to surgery
– Anticoagulant properties