Hemostasia Y PTI Flashcards

1
Q

Que es la hemostasia primaria y con que se mide

A

Vascular y plaquetaria

Se mide con el tiempo de hemorragia o metodo Ivy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Que es la hemostasia secundaria

A

Vascular+ plaquetas+ tiempos de coagulacion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Funcion de la plasmina

A

Destruye al coagulo de fibrina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Funcion de la trombiina

A

Convierte al fibrinogeno en fibrina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Factores inhibidores de la coagulacion

A

Antitrombina III
Proteina C
Proteina S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Laboratorial que evalua la via intrinseca

A

TTP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Farmaco que actua en la via intrinseca

A

Heparina no fraccionada

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Laboratorial que evalua la via extrinseca

A

TP INR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Framacos con los que se lleva un control con TP INR

A

Anticoagulantes orales - warfarina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Laboratorial que evalua la via comun de coagulacion

A

Tiempo de trombina: tiempo que tarada la trombina en convertir el fibrinogeno en fibrina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Factores de coagulacion de la via comun

A

X
V proacelerina
II protrombina
I fibrinogeno

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causa mas comun de trombocitponea por farmacos

A

Tiacidas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Agente etiologico mas comunmente asociado a PTI

A

65% se asocia con H pylori

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Clinica de PTI en base a la cantidad de plaquetas

A

<75,000 hemorragia postraumatica
<30,000 hemorragia espontaena
<10,000 hemorragia fatal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tipo de hipersensibilidad en la PTI

A

TIPO II mediada por Ac IgG CONTRA LA GLUCOPROTEINA iB y IIb/IIIa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tto urgente en PTI activa con plaquetas < 30,000

A

IgG altas dosis o metilprednisoona

+ aferesis plaquetaria

17
Q

PTI asintomatico con >30,000 plaquetas

A

Vigilancia

18
Q

Tto PTI sintomatico o plaquetas < 30,000

A

1 prednisona
2Ig G IV
3 eSPLENECTOMIA: las plaquetas tienen que estar >50,000
4. Danazol

19
Q

Que es una PTI refractaria

A

No hay respuesta a pesar de havberle realizado una esplenectomia

20
Q

Farmacos inhibidores de la trombina

A

Lepirudina

Argatroban

21
Q

Antidoto de una hemorragia por heparinas

A

Sulfato de protamina (antagonista de heparina)

22
Q

Factores de coagulacion K dependientes

A
II
VII
IX
X
C
S
23
Q

Antidoto en hemorragias por anticoagulantes orales

A

Vitamina K

24
Q

Funcion del tromboxano A2

A

Agregante plaquetario

25
Q

Donde actúa la heparina no fraccionada

A

Acelera la antitrombina III