HEMOLYTIC ANEMIA Flashcards
History & Physical
Ask about:
Dysnea on Exertion
Fatigue
Exertional Chest Pain
Jaundice
Dark Urine
Changes in stool colour
Abdominal Pain
Back Pain
Rashes / skin changes
Fevers
Night Sweats
Weight Loss
Headaches
Confusion
Recent Travel
Recent use of new medication
recent food consumption
Recent blood transfusions
Recent insect bites
History of blood related disorders
DDx
Heriditary:
G6PD
sickle cell disease
thalassemia
spherocytosis
PNH
Acquired:
MAHA
Autoimmune hemolytic anemia (AHI)
thrombotic thrombocytopenic purpura (TTP)
Hemolytic Uremic Syndrome (HUS)
DIC
Mechanical Valves
malaria
Babesiosis
Brown Recluse Spider
Workup
CBC
Reticulocyte count (>2%)
Creatinine
Urinalysis
Blood Smear
Total Bili / Direct Bili
PT / INR
LDH
Haptoglobin
Fibrinogen
Direct Antiglobulin Test / Coombs Test
Malaria:
Thick and Thin Prep
Parasitemia
HIV
Blood Cultures, Urine Cultures