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HEMATOLOGY / ONCOLOGY / IMMUNOLOGIC > DIRECT Xa INHIBITORS (NOAC) > Flashcards

DIRECT Xa INHIBITORS (NOAC) Flashcards

1
Q

Mechanism

A

Direct Inhibition of Factor Xa
No Antithrombin required

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2
Q

Apixaban Dosing

A
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3
Q

Rivaroxaban Dosing

A
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4
Q

Clearance

A

Renal
Contraindicated in patients with CrCl < 30 mL / min

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5
Q

Half-Life

A

Apixaban 7-8 hours
Rivaroxaban 11-13 hours

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6
Q

Elective Reversal

A

1-2 days prior to procedure

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7
Q

Antidote

A

PCC

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HEMATOLOGY / ONCOLOGY / IMMUNOLOGIC (16 decks)

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