Hemodynamics, Systemic Circulation Flashcards
Arteries: _____________ pressure
High
Arterioles: ____________ pressure, sm. m. walls can contract to control flow by changing resistance
Moderate
Capillaries: ____________ cross-sectional area, _____________ endothelial lining, nutrient, waste and gas exchange
Large
Single
Veins: ___________ pressure, ____________ volume, can contract to move blood to arterial side to increase BP
Low
Large
Circulatory system 1. Mitral valve->left ventricle->aortic valve 2. 3. 4. 5. Right atrium 6. 7. 8. Pulmonary vein->right atrium->circle back to 1
- Aorta (100%)
- Cerebral (15%) + coronary (5%) + renal (25%) + gastrointestinal (25%) + skeletal muscle (25%) + skin (5%) (arteries in, veins out)
- Vena cava (100%)
- Tricuspid valve->right ventricle->pulmonic valve
- Pulmonary artery (100%)-> lungs
Velocity of blood flow
V=
Can be calculated for single vessel knowing its _________________________ and ______________
Can also be determined knowing ___________________________________ and _______________
Q/A Cross sectional area Flow Total, summed cross sectional area of parallel circuits Flow
Relationships between blood flow, pressure, and resistance
Q=
Can be determined through individual vessel or segment of vessel or through entire system
CO=
Q(flow)=delta P (pressure gradient)/R (resistance)
CO (cardiac output)=(arterial pressure-venous pressure)/TPR(total peripheral resistance)
Poiseuille’s law
R=(8nl)/(pi(r)^4) n=viscosity l=length of vessel pi=pi r=vessel radius
If vascular resistances are added in ______________ then simply add individual resistances for total
If vascular resistances are added in ________________ then formula for total resistance is more complicated
Series
Parallel
Adding resistance beds in series __________________ resistance
Increases
Adding resistance beds in parallel ______________ total resistance
Decreases
Adding series resistances
Rtotal=R1 + R2 + R3 +R4 + R5
Adding parallel resistances
1/Rtotal = 1/R1 + 1/R2 + 1/R3 + 1/R4 + 1/R5 + 1/R6
When velocity is high, cross sectional area __________, density _____________ and/or viscosity is ______________ blood flow becomes _______________ turbulent
Large
Heavy
Low
More
Reynolds number
Nr=pdv/n p=density d=diameter v=velocity n=viscosity
If greater than 2000 then considered to transition from laminar to turbulent flow