Central Neural & Humoral Control Of MAP Flashcards
Local responses to excercise
Increase vasodilator metabolites
Dilation of skeletal muscle arterioles
Decrease TPR (total peripheral resistance)
Increase blood flow to skeletal muscle
Exercise central command
Increased sympathetic outflow
Decreased parasympathetic outflow (heart flow only)
Increased heart rate Increased contractility Increased cardiac output Constriction of arterioles (splanchnic and renal) Constriction of veins Decreased unstressed volume
Increased blood flow to skeletal muscle
Body anticipates exercise and _________________ sympathetic outflow and _____________ parasympathetic
CO ___________ and non active tissues _____________ resistance
Local reflexes of contracting muscle causes _______________. Tissue mass can be great enough that it could cause a large _____________ of TPR and BP if anticipatory reflexes had not already been invoked
Increases
Decreases
Increases
Increase
Vasodilation
Reduction
Decreased blood volume can be caused by
Hemorrhage
Dehydration
Loss of body fluids
Hemorrhage
___________________ venous return, preload, stroke volume, CO and BP
________________ reflexes are stimulated
_______________ reflexes are initiated
Decreased
Baroreceptors
Hormonal
Capillaries response to hemorrhage
Decreased capillary pressure
Increased fluid absorption
Increased blood volume
Increased arterial pressure toward normal
Renin-angiotensin II-aldosterone response to hemorrhage
Increased angiotensin II
Increased TPR
Increased aldosterone
Increased sodium reabsorption
Increased blood volume
Increased arterial pressure toward normal
Baroreceptor reflex to hemorrhage
Increased sympathetic outflow
Increased heart rate
Increased contractility
Increased cardiac output
Constriction of arterioles
Increased TPR
Constriction of veins
Decreased unstressed volume
Increased arterial pressure toward normal
Blood movement in upright position
Normally upright movement initiates muscle pumps which push blood upward towards the heart past valves in the limbs
If no movement then venous return accumulates in lower limbs increasing venous and capillary hydrostatic pressure
Venous pooling can result in edema and/or pressure
Reflexes will attempt to bring BP back to normal
Responses to standing
Decreased venous return Decreased CO and therefore decreased BP Baroreceptor reflex Hormonal reflex will also be initiated but probably too slow to have a significant impact Orthostatic hypotension
Standing Pooling of blood in veins Decreased arterial pressure Baroreceptor reflex Increased sympathetic outflow
Increased heart rate
Increased contractility
Increased cardiac output
Constriction of arterioles
Increased TPR
Constriction of veins
Decreased unstressed volume
Increased arterial pressure toward normal