Hemodynamics III Flashcards
What is the most common cause of Right side heart failure?
Left side heart failure
How does LHF cause RHF?
LHF causees increased pressure in pulmonary veins, capillary beds and then pulmonary arteries which increases Right heart afterload
What is the most common cause of isolated RHF?
1.Pulmonary vascular
2.Parenchymal disease
Things like Pulmonary emphysema, recurrent pulmonary thromboembolism, and interstitial lung disease
What is Cor pulmonale?
Right heart disease caused by pulmonary hypertensive diseases Things like Pulmonary emphysema, recurrent pulmonary thromboembolism, and interstitial lung disease
What are the characteristics of Acute Cor Pulmonale?
Dilation of the right heart chambers
What is the core characteristic of chronic Cor Pulmonale?
Right ventricular hypertrophy, with dilation if the workload exceeds its capacity
What do all the diseases that cause Cor Pulmonale have in common?
The cause pulmonary hypertension
What are the clinical manifestations of RHF?
!.Lower leg edema starting with the feet
- Chronic low-grade RUQ discomfort from hepatic hypertension
- Ascites (increased abdominal girth)
What are the signs of RHF?
Peripheral edema especially of the legs, hepatomegaly, ascites and JVD
What tools are helpful in diagnosing RHF
Echocardigraphy
What drugs can work to lower pulmonary blood pressure?
Sildenafil (viagra)
What is asystole?
Total lack of cardiac pumping
What is slow death from heart failure characterized by?
Progressive dyspnea due to pulmonary edema.
How does the incidence of sudden cardiac failure change with age?
Increases with age reaching its peak in the elderly
In what gender is sudden cardiac death more prevalent?
Males
What is the most common cause of sudden cardiac death?
Coronary Artery disease
2.Hypertensive heart disease
What is sudden cardiac death usually due to?
Ventricular tachyarrythmia
What is associated with Right ventricular cardiomyopathy?
Mutations in the genes for cell adhesion proteins that function in the low resistance gap junctions between myocytes
What is familial catecholeminergic polymorphic ventricular tachycrdia?
Mutation in the genes for the Ryanodine receptors
What are afterpolarizations?
tAbnormal triggered activity due to abnormal iron fluxes that interrupt repolarization
Afterdepolarizations that occur during phase 2 or 3 are called?
Early
Afterpolarization that occurs during phase 4 are called?
Delayed