Hemodynamics causes CC Flashcards
Static measures of fluid responsiveness
- CVP
- Pulmonary capillary wedge pressure
- Clinical static endpoints (heart rate, blood pressure, etc).
Dynamic measures of fluid responsiveness
- Pulse pressure variation
- Stroke volume variation
- IVC collapsibility
- Response to passive leg raise
- Fluid challenge
Causes of false positive IVC collapse
- Elevated intra abdominal pressure
Causes of false positive IVC distention
- Pneumothorax
- Pericardial effusion
Elevations in RA pressure
- Diseases of the right ventricle (eg, right ventricular infarction or cardiomyopathy)
- Pulmonary hypertension
- Pulmonic stenosis
- Left-to-right shunts
- Tricuspid valvular disease
- Cardiac tamponade
- Constrictive pericardial disease
- Restrictive cardiomyopathies
- Left ventricle systolic heart failure
- Hypervolemia
Conditions in which PAW>LVEDP
- Mitral stenosis
- Left atrial myxoma
- Pulmonary embolus
- Mitral valve regurgitation
- Pulmonary venocclusive disease
- Pulmonary vein stenosis
Conditions in which PAW
- Decreased LV compliance
- High (>25 mmHg) LVEDP
- Aortic valve regurgitation
Conditions in which PAW does not approximate PCWP (More than 1-4 mmHg difference)
- Increased pulmonary vascular resistance
- Pulmonary hypertension
- Cor pulmonale
- Pulmonary embolus
- Eisenmenger’s syndrome
Conditions that cause elevated left ventricular end diastolic pressure LVEDP
- Left ventricular systolic heart failure
- Left ventricular diastolic heart failure
- Mitral and aortic valve disease
- Hypertrophic cardiomyopathy
- Hypervolemia
- Large right-to-left shunts
- Cardiac tamponade, constrictive and restrictive cardiomyopathies
Conditions that cause a low wedge pressure
- Hypovolemia (eg, hemorrhagic shock, severe intravascular volume depletion)
- Pulmonary venoocclusive disease (variably normal or low)
- Obstructive shock due to large pulmonary embolism
Causes that would consistently overestimate cardiac output in hemodilution method
- Injectate that is warmer than programmed into the computer
Causes that would consistently underestimate cardiac output in hemodilution method
- A larger than programmed injectate
Obstructive shock
Decreased venous return:
- Cardiac tamponade
- Abdominal compartment syndrome
- Tension pneumothorax
- Increased resistance to venous return
- Tumor compression
- Venous thrombosis
- Increased PEEP/PEEP
- Pregnancy
Increased ventricular afterload:
- Increased PVR- Pulmonary embolism
- Hypertensive crisis
- Aortic dissection
Wide pulse pressure
- Thyrotoxicosis
- Arteriovenous fistula
- Aortic insufficiency
Narrow pulse pressure
- Significant tachycardia
- Early hypovolemic shock
- Pericarditis
- Pericardial effusion or tamponade
- Ascites
- Aortic stenosis
Systolic hypertension
- Increased cardiac output
- Thyrotoxicosis
- Generalized response to stress
- Anemia
- Pain, anxiety, or both
Diastolic hypertension
- Intrinsic renal disease
- Endocrine disorders
- Renovascular hypertension
- Neurologic disorders
Management options which decrease preload
- Diuretics (e.g., furosemide): decrease systemic venous tone and extracellular volume/volume overload
- Opiates (e.g., morphine sulfate) reduce sympathetic tone
- Nitrates (e.g., nitroglycerin): venous and arterial vasodilator, reduce myocardial oxygen demand
- Nesiritide: recombinant BNP that results in vasodilation and diuresis
- Ultrafiltration (volume removal)
Management options which decrease afterload
- ACE inhibitor/ARB: reduce preload and afterload
- Nitroprusside (decreases venous return and afterload)
- Nitrate
- Hydralazine
- Intraaortic balloon pump
Vasoactive drugs working on β1 receptors
- Dobutamine
- Epinephrine (LD)
- Norepinephrine
Vasoactive drugs working on α1 receptors
- Phenylephrine
- Norepinephrine
- Epinephrine
Vasoactive drugs working on β2/PDEi receptors
- Dobutamine
- Dopamine (Low Dose)
- Milrinone
- Isoproterenol
List of pulse contour analysis devices
- PiCCO
- LiDCO
- FloTrac/Vigileo
Causes of overdamped arterial line
- Clot
- Air
- kinks
- Loose connections
- Arterial spasm
- Narrow tubing
Correctable metabolic causes of depressed contractility
- Hypoxia
- Acidosis (pH<7.3)
- Hypophosphatemia
- Adrenal insufficiency
- Hypothermia
Causes of underdamped arterial line
- Catheter whip or artefact
- Stiff non-compliant tubing
- Hypothermia
- Tachycardia or dysrhythmia