Cardiology indications CC Flashcards

1
Q

STEMI: Fibrinolysis is generally preferred if

A
  • Early presentation (3 hours from symptom onset and delay to invasive strategy)
  • Invasive strategy is not an option
  • Catheterization lab occupied/not available
  • Vascular access difficulties
  • Lack of access to a skilled PCI lab
  • Delay to invasive strategy
  • Prolonged transport: (door-to-balloon) - (door-to-needle) is >1 hour
  • Medical contact-to-balloon or door-to balloon is >90 minutes
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2
Q

STEMI: An invasive strategy is generally preferred if

A
  • Skilled PCI lab available with surgical backup
  • Medical contact-to-balloon or-door-to balloon is < 90 minutes
  • (Door-to-balloon) - (door-to-needle) is < 1 hour
  • High risk from STEMI
  • Cardiogenic shock
  • Killip class is ≥ 3
  • Contraindications to fibrinolysis including increased risk of bleeding and ICH
  • Late presentation
  • Symptom onset was >3 hours ago
  • Diagnosis of STEMI is in doubt

MCQs

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3
Q

Absolute contraindications to thrombolysis

A
  • Any prior ICH
  • Intracranial neoplasm, aneurysm, AVM
  • Ischemic stroke or closed head trauma w/in 3 mo
  • Head/spinal surgery w/in 2 mo
  • Active internal bleeding or known bleeding diathesis
  • Suspected aortic dissection
  • Severe uncontrollable HTN
  • For SK, SK Rx w/in 6 mo

MCQs

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4
Q

Relative contraindications to thrombolysis

A
  • History of severe HTN, SBP >180 or DBP >110 on presentation (? absolute if low-risk MI)
  • Ischemic stroke >3 mo prior
  • CPR >10 min
  • Trauma/major surgery w/in 3 wk
  • Internal bleed w/in 2-4 wk
  • Active PUD
  • Noncompressible vascular punctures
  • Pregnancy
  • Current use of anticoagulants
  • For SK, prior SK exposure
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5
Q

Percutaneous VADs

A
  • Short-term (<14 days) therapy of cardiogenic shock
  • Bridge to procedure (e.g. longer-term VAD placement)
  • Cardiac support for complex percutaneous cardiac procedures
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6
Q

Beta blockers contraindications

A
  • HR <60
  • SBP < 100
  • CHF
  • High-grade heart block
  • Severe bronchospasm
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7
Q

Pericardiocentesis

A
  • Treatment for clinically significant pericardial tamponade
  • Occasionally diagnostic
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8
Q

Contraindications to Pericardiocentesis

A
  • Uncorrected bleeding diatheses in nonemergent setting
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9
Q

TEE contraindications

A
  • Perforated viscus
  • Esophageal stricture
  • Esophageal tumor
  • Esophageal perforation, laceration
  • Esophageal diverticulum
  • Active upper GI bleed
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10
Q

Urgent Invasive Therapy Indications for UA/NSTEMI

A
  • Heart failure or hemodynamic instability
  • Refractory angina that is not responding to maximal medical therapy
  • Life-threatening arrhythmias, including sustained ventricular tachycardia
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11
Q

Indications for Early Invasive Therapy (within 24-48 hours) for NSTE-ACS

A
  • Elevated cardiac troponins
  • Dynamic ST-segment changes
  • Glomerular Filtration Rate (GFR) < 60 mL/min
  • Left ventricular ejection fraction (LVEF) < 0.40
  • Angina that is recurring but not severe enough to demand immediate intervention
  • Recent Percutaneous Coronary Intervention (PCI) within the previous six months
  • History of myocardial infarction (MI) or Coronary Artery Bypass Grafting (CABG)
  • Diabetes mellitus
  • Intermediate or high-risk patients per clinical judgment or established risk scoring systems

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12
Q

Indications for Intra-Aortic Balloon Pump (IABP)

A
  • Cardiogenic shock not responsive to optimal medical management
  • Mechanical complications of myocardial infarction (ventricular septal defect, papillary muscle rupture)
  • Refractory ischemia or life-threatening arrhythmias
  • High-risk percutaneous coronary interventions
  • Bridge to surgery in patients with critical valvular disease
  • Bridge to transplant or left ventricular assist device in patients with refractory heart failure
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13
Q

Contraindications to Intraaortic Balloon Pump (IABP)

A
  • Severe aortic regurgitation
  • Aortic dissection
  • Significant peripheral artery disease, including iliac artery stents and iliofemoral grafts/stents
  • Active sepsis
  • Active bleeding or bleeding disorders
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14
Q

Indications for Temporary Pacemaker

A
  • Symptomatic bradycardia unresponsive to atropine
  • Hemodynamic instability from bradyarrhythmias
  • Acute anterior MI with Mobitz Type II second-degree AV block, complete AV block, or new bifascicular block
  • Overdrive pacing for drug-resistant tachyarrhythmias
  • Special situations: general anesthesia, cardiac surgery, electrophysiological studies, or specific drug overdoses
  • Inferior MI with complete AV block may not need a pacemaker if the patient is stable, heart rate is >40-50 bpm, and QRS complexes are narrow
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15
Q

Indications for Ventricular Assist Device (VAD) Placement

A
  • Cardiogenic shock refractory to medical therapy including inotropes
  • Persistent end-organ dysfunction due to low cardiac output
  • Life-threatening arrhythmias related to heart failure
  • Bridge to transplant for patients on the heart transplant list
  • Destination therapy for patients who are not candidates for heart transplantation

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16
Q

Indications for a Permanent Pacemaker (PPM)

A
  • Symptomatic bradycardia (with heart rate <40/min or significant pauses (>3 s))
  • Advanced second-degree AV block (Mobitz type II)
  • Third-degree heart block
  • Sinus node dysfunction leading to symptoms
  • Alternating bundle branch block
  • Drug-resistant tachyarrhythmias
  • Heart failure (requiring cardiac resynchronization therapy)
  • Congenital complete AV block
  • Symptomatic atrial fibrillation with significant pauses (5 seconds or more)
  • Exercise-induced second or third-degree heart block (not associated with ischemia)

Caveats: Asymptomatic third-degree heart block or Mobitz type II second-degree block might not always require a pacemaker

MCQs

17
Q

Indications for Cardiac Resynchronization Therapy (CRT)

A
  • LVEF ≤35%, in sinus rhythm, with a QRS duration ≥150 ms (LBBB), experiencing NYHA class II-IV symptoms despite optimal medical therapy. (Class IA recommendation)
18
Q

Contraindications to cardiac transplantation

A

Absolute contraindications:

  • Systemic illness with a life expectancy <2 years despite heart transplantation
  • Irreversible pulmonary hypertension with pulmonary vascular resistance >3 Wood Units (>240 dynes-sec/cm5)
  • Clinically severe symptomatic cerebrovascular disease
  • Active substance (drug or alcohol) abuse
  • Multiple demonstrations of inability to comply with drug therapy
  • Multisystem disease with severe extracardiac organ dysfunction

MCQs