Hemodynamics Flashcards
Bernoulli’s principle says that energy can be changed but not ____
Destroyed
Per Bernoulli’s principle, as ____ of fluid flow increases, there is a coexisting reduction in ____
velocity; pressure
Bernoulli’s principle states there will be an ____ in kinetic energy with a ____ in pressure at the site of an obstruction to flow
increase; decrease
Based on the conservation of energy principle: If ____ or ____ changes, there will be a change in the other energy to maintain the same level of total energy
pressure or kinetic energy
According to Bernoulli’s equation, ____ and ____ are inversely related
Velocity and pressure
If a vessel has plaque causing a narrowing, the flow velocity will ____ at the site of a stenosis so the pressure must ____
increase; decrease
What do we use Bernoulli’s principle to predict?
- The pressure drop (gradient) between two chambers
What does Bernoulli’s principle determine?
- Max and mean pressure gradients across stenotic valves
- Max pressure gradients across regurgitant valve lesions and abnormal shunt communications
What does Bernoulli’s principle estimate?
Intracardiac pressure
What is the modified Bernoulli’s equation?
∆P = 4 (v2^2 - V1^2)
What is the simplified Bernoulli’s equation?
∆P = 4(V2^2)
What does ‘P1’ stand for?
Pressure at location 1
What does ‘P2’ stand for?
Pressure at location 2
What does ‘ρ’ stand for?
Density of the blood (1.06 x 10^3 kg/m^3)
What does ‘V1’ stand for?
Velocity of location 1
What does ‘V2’ stand for?
Velocity of location 2
When is modified Bernoulli’s equation used?
Typically used with aortic stenosis when V1 is > 1.2 m/s
When is simplified Bernoulli’s equation used?
When V1 is </= 1.2 m/s
What does P1 - P2 = ?
∆P; or Q
What is the pressure in the left ventricle?
120 mmHg
What is the pressure in the aorta?
100 mmHg
What is the pressure in the arterioles?
45 mmHg
What is the pressure in the capillaries?
10 mmHg
What does ‘Q’ stand for?
Flow volume
Arterial Blood Pressure is determined by ____ and ____
Volume of blood and resistance
Equation for pressure
Pressure = flow (vol/min) x resistance
What is resistance?
The amount of pressure exerted against flow
What is distensibility?
Stretching of arteries or veins to accommodate more blood (systole)
What is elasticity?
The ability of a vessel to bounce back after being stretched
What is stroke volume (SV)? (definition)
The amount of blood pumped out of the heart per beat
What is the equation for stroke volume?
LVOTd^2 x .785 x LVOT⌄TVI
What is the normal range for stroke volume?
70-100 cc
What is cardiac output (CO)? (definition)
The amount of blood pumped by heart per minute
What is the equation for cardiac output?
SV (cc) x heart rate (HR) / 1000
What is the normal range for cardiac output?
4-8 L/min
What is cardiac index (CI)? (definition)
The cardiac output adjusted for Body Surface Area (BSA)
What is the equation for cardiac index?
Cardiac Output (CO) / BSA
What is the normal range for cardiac index?
2.4 - 4.2 L/m/m^2
What are the three resistance factors?
Viscosity, friction, and inertia (acceleration and deceleration)
What is viscosity?
The thickness of blood
What is friction?
Movement of blood against the vessels will change some pressure energy to heat
- there is some loss of the pressure energy to friction
longer, narrower vessels cause ____ friction
more
What is inertia?
property of all matter; an object at rest tends to stay at rest, an object in motion tends to stay in motion
- there is some loss of the energy pressure as inertial losses
What causes inertial losses
acceleration and deceleration
What is Poiseuille’s Law?
States that flow volume (Q) varies directly with the pressure gradient (Pi-Po) and the fourth power of the radius of the tube (r). Flow (Q) varies inversely with the length (L) of the tube and the viscosity (n) of a fluid.
What does (Pi - Po) stand for?
Pressure gradient
What does ‘n’ stand for?
Viscosity
What is Poiseuille’s law equation?
Q = (Pi-Po) πr^4 / 8nL or
∆P = Q8nL / πr^4
What is Poiseuille’s Law simplified?
- As pressure gradient ↑ flow volume ↑
- As the tube diameter ↑, flow volume ↑
- As the length of the tube ↑, flow volume ↓
- As fluid viscosity ↑, flow volume ↓
Of all of the factors that effect blood flow, the ____ of the blood vessel is the most significant!
radius