Hemodynamic Disorders Flashcards
Hemodynamics:
the flow of blood
Systole:
the blood pumping phase of the cardiac cycle.
Diastole:
the chamber filling phase of the cardiac cycle
Preload:
the ventricular wall tension at the end of diastole (degree of myocyte stretch) determined by end-diastolic volume, reflected in end-diastolic pressure
Afterload:
the resistance the ventricle must overcome to pump its contents, determined by systolic blood pressure, reflected in ventricular systolic pressure
Myocardial contractility:
inotropic state determining the portion of the force of contraction independently of preload and afterload
Compliance:
the distendibility of the ventricle, determining the ease of filling it and, indirectly, the amount of filling and hence the amount of blood pumped
Heart failure:
inability of the heart to pump sufficient blood to meet the needs of the body
B-type natriuretic peptide:
a hormone secreted in heart failure in proportion to the severity
Mitral valve prolapse:
billowing of redundant mitral valve into the left atrium during systole thromboemboli from infective endocarditis
Rheumatic heart disease:
immune-mediated inflammation of the heart, especially valves, triggered by group A streptococcal infection
Libman-Sacks endocarditis:
autoimmune inflammation of the heart valves as part of systemic lupus erythematosus.
Marantic endocarditis:
non-bacterial thrombotic endocarditis, the deposition of blood clot on heart valves.
Vegetations:
colorful misnomer for blood clots on heart valves.
Osler nodes:
pea-sized tender nodules in fingers and toes from infected thromboemboli from infective endocarditis.
Janeway lesions:
hemorrhages on the palms or soles from infected thromboemboli from infective endocarditis.
Cor pulmonale:
heart disease caused by lung disease.
Arrhythmia:
disturbance in heart rhythm due to deranged cardiac electrical signaling.
PR interval:
time from start of P wave to end of QRS, normally 120-200 ms, indicative of conduction block around AV node if prolonged.
QT interval:
time from start of QRS to end of T wave, normally <440 ms, dangerous if prolonged due to risk of ventricular tachyarrhythmias.
Atrial fibrillation:
arrhythmia of chaotic atrial activation at a rapid rate causing an irregular heart rhythm due to variable conduction through the AV node.
Ventricular fibrillation:
immediately life-threatening arrhythmia of chaotic ventricular activation at a rapid rate with lack of cardiac pumping.
Channelopathy:
heart disease of arrhythmias due to defective cardiac myocyte ion channels, usually due to genetic mutations.
Torsades de pointes:
a polymorphic ventricular tachycardia with variation in QRS size and shape, creating an outline resembling a twisted ribbon on EKG