Hemodynamic Disorders Flashcards
edema
clinical presentation of excess fluid accumulation in any tissue or body cavity
localized edema
increase in vascular permeability
generalized/systemic edema
increased hydrostatic pressure and decreased oncotic pressure
transudate
noninflammatory edema, no change in vascular permability
exudate
inflammatory edema (increased protein)
anascarca
severe edema throughout the entire body
hyperemia
increased blood volume as the result of an active process in which arteriolar vasodilation leads to increased bloodflow (inflammation)
congestion
increased blood volume occurs as a passivei process due to impaired venous outflow of a tissue
acute pulmonary edema caused by
sudden LV failure (myocardial infarction)
chronic pulmonary edema caused by
congestive heart failure
congestive liver (nutmeg liver) caused by
right-sided heart failure
petechiae
minute 1-2mm hemorrhages into skin, mucous membranes, or serosal surfaces
purpura
> 3mm hemorrhages
ecchymosis
> 1-2mm subacute hematomas
hemostasis
arrest of bloodflow
coagulation pathway
injured endothelial cells attract platelets to form primary platelet plug and activate coagulation cascade
coagulation cascade
prothrombin»_space; thrombin, fibrinogen»_space; fibrin, definitive platelet plug
fibrinolysis (clot-lysing) pathway
plasmin
anticoagulation (regulation) pathway
antithrombins, thrombomodulin, TFPI
thrombosis
process of thrombus formation
thrombus
solid mass formed by both platelet and coagulation mechanisms
tissue factor
activates clotting cascade
arterial thrombosis
atherosclerosis
superficial venous thrombosis (thrombophlebitis)
saphenous veins, varicose veins
deep vein thrombosis (phlebothrombosis)
femoral, popliteal, posterior tibial veins
blood clot
coagulation cascade only
laminar flow
platelets and cells in center of vessel, plasma in periphery
turbulent flow (stasis)
increased chance of contact between platelets and vessel wall