HIV drugs Flashcards

1
Q

elvitegravir (EVG)

A

INSTI

SE:
nausea/diarrhea
upper resp tract infections, bronchitis
back/joint pain
UTI
drug interactions
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2
Q

raltegravir (RAL)

A

INSTI

SE:
high creatinine kinase
myositis, rhabdomyolosis
skin rash
hypersensitivity
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3
Q

dolutegravir

A

INSTI

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4
Q

maraviroc

A

FI

binds ccr5

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5
Q

enfuvirtide

A

FI

binds gp41

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6
Q

ritonavir (RTV)

A

PI

CYP34A inhibitor
combo w/other PI
induces own metabolism

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7
Q

atazanavir

A

PI

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8
Q

darunavir

A

PI

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9
Q

fosamprenavir

A

PI

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10
Q

indinavir

A

PI

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11
Q

nelfinavir

A

PI

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12
Q

squinavir

A

PI

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13
Q

tipranavir

A

PI

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14
Q

efavirenzs (EFV)

A

NNRTI

most potent

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15
Q

delavirdine

A

NNRTI

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16
Q

etravirine

A

NNRTI

17
Q

nevirapine

A

NNRTI

18
Q

rilpivirine

A

NNRTI

19
Q

zidovudine (AZT)

A

NRTI

glucuronidation

20
Q

abacavir (ABC)

A

NRTI

alcohol dehydrogenase
hypersensitivity (test HLAb5701)

21
Q

tenofir disproxil fumarate (TDF)

A

NRTI

22
Q

emtricitabine (FTC)

A

NRTI