Hematology Review Flashcards
MCV means what?
Mean corpuscular volume which indicates the SIZE of the red blood cell
MCH means what/
Mean corpuscular hemoglobin which indicates the COLOR of the of the red blood cell
a low MCV is called what?
microcytic
a low MCH is called what?
hypochromic
a high MCV is called what?
Macrocytic
a high MCH is called what?
Hyperchromic
what does RDW means?
Red cell distribution width
which means the variation of the RBCs
what is the lab test that measures stored iron?
serum ferritin
what does serum iron measure?
iron in the circulation
transferrin is also called what?
total iron binding capacity
lead toxicity looks just like what anemia?
iron deficiency anemia
what are expected lab findings for iron deficiency anemia?
MCH, MCV, serum iron, serum ferritin, TIBC, RDW
microcytic, hypochromic anemia
low serum iron and low serum ferritin
increase TIBC
increased RDW
what are good sources of iron?
liver, lentil soup, spinach, clams, red beans, rice, oysters
with the diagnosis of iron deficiency anemia, what is the recommended amount of time a patient to be on iron supplementation?
4 to 6 months
what type of cells (MCV and MCH) are common in a patient that has thalassemia?
microcytic, hypochromic anemia
What lab findings are common in a patient with thalassemia?
Low hct/hgb
low MCV/MCH
Normal RDW
normal serum iron, ferritin, TIBC
What kind of anemia has a normal MCV and MCH (normochromic, normocytic) ?
anemia of chronic disease
What are the two most common macrocytic anemias?
B12 deficiency, pernicious anemia, and folate deficiency
what is the the recommended supplement replacement for B12 deficiency?
B12 1000 mg to 2000 mcg daily
what is the recommended supplement replacement for Folate deficiency?
1 mg daily
The diagnosis of thrombocytopenia is based off of what lab?
Platelets being less than 150,000
what is the treatment for a patient with thrombocytopenia?
Prednisone 4-6 week treatment, referral to a hematologist.
minimize activity to prevent injury
reed sternberg cells are associated with what type of cancer blood disorder?
Hodgkin’s lymphoma
what is the most sensitive test for iron deficiency anemia?
serum ferritin
what is the gold standard test for sickel cell anemia and thalassemia?
hemoglobin electrophoresis
what does koilonychia ?
spoon shape nails
For women of childbearing age, what is the recommended folic acid supplementation replacement in mcg? what about mg?
400 mcg or 0.4mg
Glucose 6 phosphate dehydrogenase deficiency (G6PD deficiency) anemia is more common in what gender and race?
males, has only one x chromosome.
Common in African American males or Mediterranean descent (some asians)
sickle cell anemia is what type of genetic disorder?
autosomal recessive disorders
what is the gold standard test for diagnosing sickel cell anemia?
hemoglobin electrophoresis
what are common symptoms of iron deficiency anemia?
hair loss, dry rough skin, pallor, brittle nails, fatigue, and tachycardia
