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First Aid CK Rapid Review ❤️ > Hematology / Oncology > Flashcards

Hematology / Oncology Flashcards

1
Q

4 causes of Microcytic Anemia

A

TICS

Thalassemia
Iron Deficiency
Anemia of Chronic Disease
Sideroblastic Anemia

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2
Q

Elderly man with hypochromic, microcytic anemia is asymptomatic. Diagnostic Test?

A

Fecal Occult blood test and sigmoidoscopy

Suspect Colorectal cancer

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3
Q

Precipitants of hemolytic crisis in pt with G6PD deficiency

A

Sulfonamides
Antimalarial drugs
Fava Beans

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4
Q

Most common inherited cause of hypercoagulability

A

Factor V leiden Mutation

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5
Q

Most common inherited bleeding disorder

A

Von Willebrand’s Disease

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6
Q

Most common inherited hemolytic anemia

A

Hereditary Spherocytosis

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7
Q

Pure RBC aplasia

A

Diamond-Blackfan Anemia

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8
Q

Anemia associated with abscent radii and thumbs, diffuse hyperpigmentation, cafe au lait spots, microcephaly and pancytopenia

A

Fanconi’s Anemia

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9
Q

Medications and Viruses that lead to aplastic anemia

A 
Chloramphenicol
Sulfonamides
Radiation
HIV
Chemo Agents
Hepatitis
Parvovirus B19
EBV
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10
Q

Distinguish Polycthemia Vera from 2 Plycythemia

A

Both have increase Hematocrit and RBC mass

Polycythemia Vera should have NORMAL 02 saturation and low erythropoietin levels

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11
Q

Thrombotic Thrombocytopenic Purpura (TTP) pentad?

A

FAT RN

Fever
Anemia
Thrombocytopenia
Renal Dysfunction
Neurologic Abnormalities
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12
Q

HUS Triad

A

Anemia
Thrombocytopenia
Acute renal failure

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13
Q

Treatment for TTP?

A

Emergent Large Volume plasmapheresis
Corticosteroids
Anti-Platelet drugs

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14
Q

Tx for Idiopathic Thrombocytopenic Purpura (ITP) in children

A

Usually resolves spontaneously

May require:
IVID and/or Steroids

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15
Q

Which of the following are increased in DIC:

Fibrin Split products
D- Dimer
Fibrinogen
Platelets
Hematocrit
A

Fibrin split products increase
D-dimers increase

Platelets Decrease
Fibrinogen Decrease
Hematocrit Decrease

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16
Q

8 y/o presents with hemarthrosis and increase PTT with normal PT and bleeding time. Diagnosis? Tx?

A

Hemophilia A or B; consider desmopression, or factor VIII or IX Supplements

17
Q

14 y/o girl presents with prolonged bleeding after dental surgery and with menses, normal PT, normal or increase PTT, and increase bleeding time. Diagnosis? Tx?

A

Von williebrand’s disease; treat with desmopressiin, FFP or Cryoprecipitate

18
Q

60 y/o AA man presents with bone pain. Workup for multiple myeloma might reveal?

A

Monoclonal gammopathy
Bence Jones proteinuria
Punched out lesions on Xray of skill and long bones

19
Q

Reed-Sternberg Cells

A

Hodgkin’s Lymphoma

20
Q

10 y/o boy presents with fever, weight loss, and night sweats. Exam shows anterior mediastinal mass. Suspected diagnosis?

A

Non-Hodgkin’s Lymphoma

21
Q

Microcytic Anemia with decrease serum iron, decrease total iron-binding capacity (TIBC) and normal or increase ferritin

A

Anemia of Chronic Disease

22
Q

Microcytic Anemia with decrease serum iron, decrease ferritin and increase TIBC

A

Iron Deficiency Anemia

23
Q

80 y/o man presents with fatigue, lymphadenopathy, splenomegaly, and isolated lymphocytosis. Suspected diagnosis

A

Chronic Lymphocytic Leukemia (CLL)

24
Q

The Lymphoma equivalent of CLL

A

Small Lymphocytic Lymphoma

25
Q

Late, Life-threatening complicatoin fo chronic myelogenous leukemia (CML)

A

Blast Crisis (Fever, Bone Pain, Splenomegaly, Pancytopenia)

26
Q

Auer rods on blood smear

A

Acute myelogenous leukemia (AML)

27
Q

AML Subtype associated with DIC

A

M3

28
Q

Electrolyte changes in Tumor lysis syndrome

A

Decrease
- Ca

Increase

  • K
  • Phosphate
  • Uric Acid
29
Q

Treatment for AML M3

A

Retinoic Acid

30
Q

50 year old man presents with early satiety, splenomegaly, and bleeding. Cytogenetics show t(9,22). Diagnosis?

A

CML

31
Q

Heinz Body

A

Intracellular inclusions seen in thalassemia

G6PD
Post-Splenectomy

32
Q

AR disorder with a defect in the GP IIB / IIIa platelet receptor and decrease platelet aggregation

A

Glanzmann’s Thrombasthenia

33
Q

Virus associated with aplastic anemia in pt with sickle cell anemia

A

Parvovirus B19

34
Q

25 year old AA man with sickle cell anemia has sudden onset of bone pain. Pain management for crisis

A

02
Analgesia
Hydration
Transfusion

NEED TO TO MORPHINE

35
Q

Significant cause of morbidity in thalassemia pt. Treatment?

A

Iron Overload

use Deferoxamine

First Aid CK Rapid Review ❤️ (15 decks)

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