Hematology and Oncology Flashcards

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1
Q

How do you reverse thrombolytic overdose?

A

Aminocaproic acid

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2
Q

Reverse Heparin over dose

A

Protamine sulfate

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3
Q

Reverse Warfarin over dose

A

Vitamin K and fresh frozen plasma

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4
Q

Translocation in Burkitt’s lymphoma

A

t(8;14); c-myc with Heavy chain Ig

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5
Q

Mantle Cell lymphoma translocation

A

t(11,14); cyclin D1 with heavy chain Ig

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6
Q

Follicular lymphoma translocation

A

t(14,18); Heavy chain Ig with bcl-2

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7
Q

APL translocation

A

t(15;17)

Fusion of PML-RARa receptor (retinoic acid receptor)
Tx: ATRA

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8
Q

CML translocation

A

t(9;22) Ph chromosome (bcr-abl)
Tx: Imatinib

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9
Q

Stain for Hairy Cell Leukemia

A

Stains TRAP (tartrate resistant acid phosphatase)

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