hematology 4.2

Question 1

Where does Heme biosynthesis occur?

Answer 1

mitochondria and cytoplasm

Question 2

a physicochemical phenomenon which describes the increased capacity of blood to carry CO2 under conditions of decreased haemoglobin oxygen saturation.

Answer 2

The Haldane effect

Question 3

1. affinity of carbon monoxide for hemoglobin is 245 times that of oxygen
2. Sulfhemoglobin is formed by the reversible
   oxidation of heme iron to the ferric state.

A. Both are correct
B. Neither are correct
C. Only 1 is correct
D. Only 2 is correct

Answer 3

B. Neither are correct

Question 4

A third function of hemoglobin involves the binding,

inactivation, and transport of nitric oxide (NO)

Answer 4

Nitric oxide transport

Question 5

Globin are made from the _____?

Answer 5

Ribosomes

Question 6

What is heme and globin?

Answer 6

Heme- heme group which is composed of
iron + protoporphyrin IX

Globin- Protein component

Question 7

TRUE OR FALSE

6 oxygen molecules will attach to your hemoglobin
structure

Answer 7

FALSE (4)

Question 8

Greek Name and # of AminoAcids

1. δ
2. ζ
3. γA

Answer 8

1. Delta - 146
2. Zeta - 141
3. GammaA - 146 (136:alanine)

Question 9

What is the complete hemoglobin structure?

Answer 9

Spherical, has 4 heme groups attached to 4 polypeptide chains and may carry up to 4 molecules of oxygen

Question 10

normal lifespan of RBCs

Answer 10

90-120 days