hematology 4

Question 1

Damaging effects of Heme are limited in 2 ways

Answer 1

1. By BINDING

2. By DEGRADATION

Question 2

Also referred to as mechanical hemolysis

Answer 2

Intravascular

Question 3

Light pink structure found in the liver and red bone marrow

Answer 3

Macrophages

Question 4

TRUE OR FALSE

RBC has an average size of 7.5-8.5 um

Answer 4

FALSE

Question 5

RBC destruction that takes place in the mononuclear
phagocytic system (spleen, liver, etc)

Answer 5

Extravascular hemolysis

Question 6

What are the 2 causes of hemolysis?

Answer 6

1. Intrinsic to the RBC (mostly Hereditary)

2. Extrinsic to the RBC (mostly acquired)

Question 7

The RBC removal occurs in three main
reticuloendothelial cell organs for phagocytosis
by the macrophage

Answer 7

1. Spleen
2. Liver
3. Bone marrow

Question 8

How the doctor would assess severity of intravascular

hemolysis?

Answer 8

Measures

1. Haptoglobin
2. Methaemalbumin
3. haemopexin

Question 9

TRUE OR FALSE

Severe intravascular hemolysis is when haptoglobin is depleted and the haemopexin may be normal or only slightly lowered.

Answer 9

FALSE

Severe intravascular hemolysis is when haptoglobin is depleted and the haemopexin is low or absent.