Hematology 4 Flashcards
Define what thalaseemia is , describe what beta thalassemia is, describe how thalassemia , beta thalassemia and alpha thalassemia can be diagnosed. Explain the paramaters used to classify thalaessemia
25-29
Describe what sick beta thlassemia is and what HbE thalassemia is
slide 50,51
Describe the differnet types of globin chains ,classify them geneticallly, give details the gene switching that occuers in haemoglobin synthsis, and deasribe the strcture of the three types of haemaglobin found in an adult. Describe general structure of . a globin chain
s 10-15, 26
Explain how thalassemnia najor can be treated
s 37-46
Desceibw rhw peoblems asssociated with treatment in developing countries, and how scree and prevention is carried out for beta thalassemia
slide 56,57
Describe how iroon overload can be monitored
slide 48,49
Recall adv and disadv of usiing different iron chelators ,
slide 47
Describe shape og Hb-oxygen dissocation cruve and explain ohw it can be affected
slide 15-20
Describe the structure and synthesis of haem
slide 7-9
Give the dteails of the function and features of haemaglobin and red blood cells
slide 3-6
What is the most common inherited single gene disorder worlwide, and describe distribution (20 sec)
slide 22,23
Describe how beta thalassemia trait and beta thalassemia major can be diagnosed, describe what they are also
30-37,53
Explain what alpha thalassemis is and the features of the different types, describe how different types can be diagnosed
slide 52,54,55
