Hematology Flashcards

1
Q

dense granules (CASH)

A

Ca
ADP
5-HT
Histamine

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2
Q

alpha granules

A

vWF
fibrinogen
fibronectin
platelet factor 4

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3
Q

lipid A binds ___ to initiate shock

A

CD14

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4
Q

mastocytosis associated with ___ mutation

A

c-kit

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5
Q

Hb travel speeds

A

A fat santa claus

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6
Q

direct coombs

A

patient RBCs and serum

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7
Q

indirect coombs

A

only patient serum

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8
Q

AT inhibits which 5 factors

A

VII, IX, X, XI, XII

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9
Q

acanthocytes seen when

A

vitamin E deficiency

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10
Q

echinocytes (burr cells) seen when

A

PK deficiency

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11
Q

orotic aciduria

A

megaloblastic anemia
UMP synthase deficiency

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12
Q

cold AIHA seen with what pathogens

A

mycoplasma
EBV

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13
Q

warm AIHA seen with what conditions

A

SLE
CLL

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14
Q

AIP Tx

A

hemin
glucose

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15
Q

PCT Tx

A

hydroxychloroquine

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16
Q

cryoprecipitate contains ___ and ___

A

fibrinogen
VIII

17
Q

reed sternberg cells are ___ and ___+

A

CD15
CD30

18
Q

most common HL

A

nodular sclerosis

19
Q

marginal zone lymphoma

A

t(11,18)
chronic inflammation

20
Q

ALL

A

t(12,21)

21
Q

richter transformation

A

CLL&raquo_space;> diffuse large B cell lymphoma

22
Q

DIC is a common presentation with ___

A

AML

23
Q

pseudo-pelger-huet anomaly seen in ___

A

CML
(bilobed duet neutrophil)

24
Q

lytic skull lesion or mastoid mass

A

langerhan cell histiocytosis

25
Q

how to reverse thrombin inhibitors

A

idarucizumab

26
Q

how to reverse Xa inhibitors

A

andexanet alfa

27
Q

carmustine treats ___

A

GBM