HEMATOLOGY

Question 1

SEGMENTED NEUTROPHILS

Answer 1

Key identifying features: 2-5 lobes, no visible chromatin in the thinnest filaments. Increased in bacterial infections.
Function: First line of defence against bacteria, function via phagocytosis of bacteria
Increase seen in bacterial infections

Question 2

BAND NEUTROPHIL

Answer 2

Key identifying features: The indentation of the nucleus is more than 50%, chromatin is seen in the thinnest part.
Same function as neutrophils, they are just the immature form, increases seen in bacterial infection.

Question 3

EOSINOPHIL

Answer 3

Key identifying features: 2-3 lobes, pink/orange staining granules
Function: Ingest and detoxify foreign protein; help turn off immune reactions; increase with allergies

Question 4

BASOPHIL

Answer 4

Key identifying features: Dark staining purple to black granules overlapping the nucleus
Function: Contain histamine and other proteins that play a role in an IgE allergic reactions. Also involved in control of parasitic infections.

Question 5

LYMPHOCYTES

Answer 5

Key identifying features: Round nucleated cells that are slightly larger than RBCs.
Function: Provide antibody and cell-mediated immunity
Increases are seen with viral infections, decreases are seen in immunodeficiency or drug therapy

Question 6

MONOCYTES

Answer 6

Key identifying features: Blue-grey cytoplasm with brain like convulsions
Functions: Destroy pathogens by phagocytosis; first line of defence in the inflammatory process.
Increased can be seen with disease

Question 7

NEUTROLPHILIC MYELOCYTE

Answer 7

Key identifying features: Round to oval to one side, flattened side near Golgi body, no indentation

Question 8

METAMYELOCYTE

Answer 8

Key identifying features: Kidney shaped, indentation is less than 1/2 of the width of the nucleus

Question 9

RBCS

Answer 9

non nucleated, biconcave discs, 6-8 microns, function to carry oxygen to cell and CO2 away from cells