hematologic cancers

Question 1

manifestations of thrombocytopenia

Answer 1

stem cell disorder with bone marrow
vascular occlusion
headaches
enlarged spleen
hemorrhage
asymptomatic
low platelet count found incidentally
easy bruising, heavy menses, petechiae on trunk or extremities

Question 2

leukemia signs and symptoms

Answer 2

tiredness
pale complexion
fatigue
dyspnea
repeated infections
mouth sores
fever
sweats
coughing
polyuria with irritation
infected scratches or cuts
boils
increased bruising and bleeding
renal dysfunction
tumor lysis
dic

Question 3

lab tests for leukemia

Answer 3

leukocyte count
absolute neutrophil count
hematocrit
platelets
creatnine
electrolyte
coagulation and hepatic function tests

Question 4

chronic lymphocytic leukemia

Answer 4

malignancy of b lymphocytes (fevers, night sweats, unintentional weight loss)
common in older men above 60
2-14 years

Question 5

chronic lymphocyic leukemia s&s

Answer 5

night sweats weight loss fevers
normal or low erythrocyte and platelet
early sign high lymphocyte
lymphoadenopathy
enlarges liver or spleen
later stage thrombocytopenia

Question 6

chronic lymphocytic anemia treatment

Answer 6

early stage watch and wait
later stage treat with tyrosine kinase inhibitors
drug interactions with corticosteroids anticonvulsants
bacterim prophylaxis
chemotherapy
monoclonal antibody
IV immunoglobins for recurrent infection
hemopoetic stem cell transplant

Question 7

hodgkins lymphoma physical and lab findings

Answer 7

reed steinberg test
mediastinal mass on x ray
b symptoms
pet scan
ct of chest
liver and renal studies
est
symptoms related to organ compression
compression of trachea
cough
pleural effustion
abdominal pain
herpes zoster
severe pain on ingestion of alcohol
b symptoms

Question 8

tumor lysis syndrome lab and physical findings

Answer 8

rapid destruction of large number of cells
elevated serum phosphate causes calcium to go down causing hypocalcemia
hyperuricemia
hyperphosphatemia
hyperkalemia
hypocalcemia
occurs 24-48 hours after chemo and may persist 5-7 days
physical findings- presence of abdominal pain, dysuria, oliguria, flank pain, hematuria
hypocalcemia- anorexia, vomiting cramps spasms altered mental status tetany
hyperkalemia- weakness and paralysis

Question 9

cbc counts

Answer 9

sodium- 135-145
potassium 3.5-5
bun 6-24
creatine 0.5-1.1 women 6-1.2 men
rbc men 4.5-6 women 4-5
wbc 4.5-11
platelet 15-=45-
hematocrit 42=5- men 36-45 women
hemoglobin 14-17 men 12-15 women