hematologic alteratations Flashcards

1
Q

Primary regulatory hormone for red cell

production

A

EPO

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2
Q

Organ responsible for red cell production

A

Erythron

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3
Q

8 μm in diameter, anucleate, discoid
in shape, and extremely pliable in order to traverse
the microcirculation successful

A

mature red cells

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4
Q

male anemic

A

<130g/L

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5
Q

female anemic

A

120g/L

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6
Q

10-15% blood loss (500-700ml)

A

hypotension and decreased organ perfusion

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7
Q

> 30%(1500ml)

A

postural hypotension*, tachycardia

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8
Q

hypovolemic shock including confusion, dyspnea, diaphoresis, hypotension, and tachycardia

A

> 40%

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9
Q

Palmar crease – full palm is very pale or is as pale
as its surrounding areas; when this occurs the Hgb is
already ____

A

<7g/dL or <70g/L

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10
Q

ACUTE HEMOLYSIS

A

o Acute back pain
o Free hemoglobin in the plasma and urine
o Renal failure

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11
Q

Hemoglobin<70-80 g/L

A

severe anemia

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12
Q

severe anemia tx

A

blood transfusion

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13
Q

If the cause of anemia is acute blood

loss, the red cell production rate

A

increases (positive feedback)

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14
Q

A reticulocyte response less than two to three

times normal indicates an

A

inadequate marriw response

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15
Q

reflects absolute or relative marrow failure

A

hypoproliferative

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16
Q

Ri >= 2.5

A

Hemolysis/ hemorrhage

17
Q

Is defined as an increase in the hemoglobin above
normal. This increase may be real or only apparent
because of a decrease in plasma volume (spurious or
relative)

A

POLYCYTHEMIA

18
Q

Petechiae pin point red rashes

A

Low counts of platelets

19
Q

loss of 80> cc of blood per

cycle

A

menorrhagia

20
Q

Normal platelet count:

A

150,000-350,000/μL

21
Q

thrombocytopenia platelet count

A

<100,000/μL

22
Q

a measurement of platelet
function, is abnormally increased if platelet
count is <100,000/μL; injury or surgery may
provoke excess bleeding

A

bleeding time

23
Q

Thrombocytopenia- dengue

A

Increased destruction

24
Q

Clopidogrel is avoided

A

I wk to 10 days

25
Q

Aspirins are stopped

A

atleast 3 days to 1 week

26
Q

major risk factor for arterial thrombosis

A

atherosclerosis

27
Q

Pt (extrinsic )

A

1,2,5,7,10

28
Q

Aptt (intrinsic)

A

11,9,8,19,5,2

29
Q

is the most important part in identifying lymphadenopathies on a patient

A

palpation

30
Q

Most frequent site of lymphadenopathy

A

neck

31
Q

Supraclavicular lymph nodes

A

tb, sarcoidosis, toxoplasmosis

32
Q

Tuberculosis

A

mesenteric lymphadenitis

33
Q

comparably accurate (65– 90%) in the diagnosis of metastases to cervical lymph nodes

A

ct, mri

34
Q

has been used to determine the long (L) axis, short (S) axis, and a ratio of long to short axis in cervical nodes.

A

ultrasonography

35
Q

Fine-needle aspiration should be reserved for

A

thyroid nodules

36
Q

Current procedure of choice for routine assessment

of spleen size

A

ultrasound

37
Q

Spleen

A

LUQ

38
Q

A common therapeutic indication for splenectomy is

A

TRAUMATIC OR IATROGENIC SPLENIC RUPTURE

39
Q

occurs after immediate postsplenectomy
period, but within 2–3 weeks, blood cell
counts and survival of each cell lineage are
usually normal

A

leukocytosis (up to 25,000/μL) and

thrombocytosis (up to 1 × 106 /μL)