HEMA MTAP RETAKE Flashcards
Lazy Leukocyte syndrome
NEUTROPHIL
Variation in erythrocyte size
Anisocytosis
Variation in erythrocyte shape
Poikilocytosis
Average diameter of a normal RBC
7.2
Four stages (maturation sequence) for thrombocyte
Megakaryoblast
Promegakaryocyte
Megakaryocyte
Thrombocyte
as a blood cell matures, the N:C ratio?
Decrease
If a child ingested rat poison, test is for:
Prothrombin Time
“Prothrombin is a protein produced by the liver that helps blood to clot. Rat poisons, particularly those containing warfarin or similar substances, work by interfering with vitamin K and inhibiting the production of clotting factors, which can lead to bleeding issues.”
Megaloblastic Anemia: size, color
Macrocytic, Normochromic
A patient with a severe decrease in factor X activity would demonstrate normal:
Bleeding Time
If a blood smear is too long:
INCREASE THE ANGLE OF THE PUSHER SLIDE
Normal range for reticulocyte:
0.5-2.0
For maturation sequence of new segmented neutrophil, what is the first sequence?
Myeloblast
Increased amount of 2,3 DPG
Decrease oxygen affinity
von willebrand disease affected which test
Bleeding Time
Therapeutic Range for APTT
60-100
Which factor is a Labile factor
Factor V
Which parameters are calculated rather than directly measured in CBC:
HEMATOCRIT AND RDW (erythrocyte distribution width)
Vitamin K dependent factors:
The prothrombin group factors II, VII, IX, and X are called vitamin K-dependent factors.
Which maturation sequence in segmenters is Azurophilic/Primary/Non-specific granules:
Promyelocyte
Acantocytes:
ABETALIPOPROTEINEMIA
Normal color of neutrophil cytoplasm:
Tan or PINK
Operational body iron is normally contained:
Hemoglobin
The reagent used in the traditional sickle cell screening test is:
Sodiumdithionide
Microspherocytes are found in:
Hemolytic Disease or Newborn
Folded Membrane
Washington Disease
Stain that stains more crystal violet?
Methylene Blue
Acquired platelet Disorder
UREMIA
Lysosomal storage disease characterized by macrophages striated cytoplasm with store problem in the storage of glucocerebrosidase:
Gaucher’s Disease
If you are grading changes in erythrocytic size or shape using a scale of 0 to 4+ and many erythrocytes deviate from normal per microscopic field, the typical score would be:
3+
Myeloid and monocytic-myelocytic:
Fab M4
Overanticoagulation affects:
Hematocrit
Programmed cell death:
Apoptosis
How is platelet satellitism corrected:
REDRAW BLOOD SAMPLE IN A BLUE TOP (CITRATE) TUBE INSTEAD OF EDTA
CLP is associated with:
LEUKOCYTE
Decrease ESR:
POLYCYTHEMIA
This organ is the site of sequestration:
SPLEEN
Which of the following morphologic changes occurs during normal blood cell maturation:
CONDENSATION OF NUCLEAR CHROMATIN
First CD marker/s to appear during the first stage of T-cell development:
CD2
Increase in RDW and MCV:
Megaloblastic Anemia
an erythrocyte histogram, the erythrocytes that are larger than normal will be to the _____ of the normal distribution curve
RIGHT
Once sufficient blood has been collected, when does the tourniquet will be withdrawn:
Before withdrawing the needle
Acute Myelomonocytic leukemia is FAB:
M4
Used for the diagnosis of FAB M6:
Periodic Acid-Schiff
Auer rods are characterized as:
Fused Primary Granules
Niemann-Pick:
Macrophages
Hairy cell leukemia:
TARTIC PERSISTANT ACID PHOSPHATASE
Major aggregation of blow cell cytometry:
UTILIZES MONOCLONAL ANTIBODIES
Hemoglobin electrophoresis, muuban ug migrate si C ug A2:
SN, F, N, A
Compute first the WBC count:
250
Which of the following is not true in terms of platelet characteristic:
all of them are true except letter D – because they are normally found circulating in their active form
Compute first the WBC count ayha ang corrected WBC count:
9,600
Excessive rouleux is correlated with increase in:
ESR
Expected lifespan of an RBC, how many months is the 120 days:
3-4 months
If a newborn has a hemoglobin H it would demonstrate 30% of:
FETAL
Compute for the MCV, MCHC:
Microcytic, Hypochromic
68 cells counted x 1000
68,000
Morphological characteristic associated with Chediak-Higashi:
GIANT LYSOSOMAL GRANULES
Rule of three: multiply si hemoglobin by three:
Hematocrit
Precursor for neutrophil
BAND
Massive automated blood cell counter is based on:
Impedance principle
All of the following are true in iron deficiency anemia except:
Decrease in RBC
Platelet precursor:
Megakaryocyte
Aspirin affects:
Inhibition of cyclooxygenase
Accept or Reject: Clotted specimen for hematology
Reject
Which of the following method is not used to detect in differentiating WBCs: *how do you determine you WBC?
Through conductivity of measurement using the choice A, B and C except letter D – for HgB
How do compute for MCV?
HCT DIVIDED BY RBC MULTIPLY BY 100.
Why do we view specimen under the 10x objective:
All of the Above
Warm bodies:
NAD
Which organ do T-lymphocytes matures
Thymus
Corrected WBC count
9,800
Bone Marrow aspirate is >90% blasts:
ACUTE LEUKEMIA
Lipemic sample *which is affected?
Ang nay HgB: MCHC
Prominent morphologic feature of lead poisoning:
Basophilic Stippling
Beta is chromosome:
11
Which of the following is not a function of Tlymphocyte:
SYNTHESIZE ANTIBODY
Clotted sample and which one is most affected:
Platelet Count
Auto-agglutination of red cell at room temperature can dissolve in which of the following:
ALL OF THESE – it will result in low RBC count, high MCV, low HCT
Sickle cell anemia, valine is substituted as glutamic acid at the sixth position on the ___ chain of the hemoglobin molecule:
BETA
BITE CELLS:
G6PD
DIC is associated with:
ACUTE PROMYELOCYTIC LEUKEMIA (FAB M3)
Polycythemia vera is characterized as an absolute decrease in:
Total Red Cell Mass
If naa’y Philadelphia chromosome, prognosis is?
BETTER
Which of the following is not associated with a causing falsely low ESR:
Column is Slanted
What combination of reagent is used to measure hemoglobin:
POTASSIUM FERRICYANIDE AND POTASSIUM CYANIDE
What are the reason RBCs are so bright red:
ACIDIC
LAP Score:
Polycythemia Vera
Principle of impedance:
AMPLIFICATION OF ELECTRICAL CURRENT OF BLOOD CELLS
To evaluate normal platelet numbers
8-20 platelet per fields
after applying the tourniquet –
FALSELY ELEVATED HEMOGLOBIN (would occur if tourniquet is more than one minute –Hemoconcentration)
Most preferred site for bone marrow aspiration biopsy for adult
ILIAC CREST (Superior Iliac Crest)
For capillary collection for newborns, which of the following lancet should be used to avoid penetrating the bone –
1.75 mm
Which of the following needs to be collected in a lavender top tube
CBC
A phlebotomy is preparing her collection basket on June 14. Expiration of the tube is on June 2007. Can she use the tubes?
YES, THE TUBE EXPIRES ON THE LAST DAY OF THE MONTH
If the blood is drawn quickly from the vein, the vein will have tendency to
Collapse
All of the following are universal precautions except
PRECAUTION LABELS ARE IN ANY PATIENT SPECIMEN
Order of draw for skin puncture blood specimen –
ALWAYS START WITH A SMEAR > EDTA > SERUM
Five-part differential
NEUTROPHIL enumerate the three granulocyte, LYMPHOCYTE AND MONOCYTE
Shift to the right
– 1, 2 and 3 (BODY TEMPETURE INCREASE, 2,3 DPG AND CO2 (opposite si pH)
Microcytic red blood cell are seen in
All of the Above
Macrocytic red blood cell are seen in following except
HEMOLYTIC ANEMIA(RBC in HA: normochromic, normocytic)
Conditions wherein rouleux formation is seen
ALL
Which of the following characterizes a bronze cell –
Increase MCHC
What do you call the remnants of chromatin found in severe anemia (SA) –
Howell JOLLY BODIES
Most valuable and reliable criterion for identifying mature and immature WBC
Nuclear Characteristic
Primary granules containing micro peroxidase firs appear in what myelocytic stage
Promyelocyte
In what stage do neutrophilic granules appear
Myelocyte
An important marker associated with T-lymphocyte
CD2 and CD3; bsta T-lymphocyte single digit gyd na sya
✓ CD19 – B cell
✓ CD34 & 45 – Hematopoietic stem cells and 45 specific for WBC
✓ CD56 – NK Cells
✓ Lymphocyte – T cells
Cell producing antibodies
Plasma Cell
Cells in acute inflammation
Neutrophils
80μm in size in a cell transit in chronic inflammation –
Mature Macrophage
Parasitic infection and allergies
Eosinophils
Diffused primary granules seen in myeloblast
Auer ROds
Cell lineage associated with endomitosis
Thrombocytes
The number of inversions needed to properly mixed pseudocitrate with a blood specimen
3-4
What combination of reagents is used to measure hemoglobin
POTASSIUM FERRYCYANIDE AND POTASSIUM CYANIDE
The slowest moving hemoglobin on an alkaline electrophoresis at pH 8.6 is
A2, C, E and S
Which of the following is not associated with causing a falsely low ESR
Column is Slanted
To best preserve cellular morphology, differential smears from EDTA specimen should be made no more than how many hours after collection
5 hours
The patient has PD, how do you correct this problem for your blood smear
INCREASE THE ANGLE OF THE SPREADER SLIDE
Components of Wright stain
Methylene Blue & Eosin
What is the depth of the hematocytometer
0.10
Which of the following would not be the cause of falsely low high MCHC of 38.3 in an automated instrument
Hereditary Spherocytosis
What is the principle of the automated impedance counters
AMPLIFICATION OF ELECTRICAL CURRENT BY CELLS
Which of the following is not associated with the increase of inaudible and decrease surface area of volume ratio
Beta Thallasemia
If you have a clotted EDTA, unsa ang pwede matest –
Hemoglobin Test
Excessive centrifugation causes
Falsely low results
Other name for hematocrit
Packed red blood cell volume
Gaucher
1,2 AND 3 (chicken scratch, wrinkled tissue paper, onion skin-like)
HAIRY CELL LEUKEMIA
LYMPHOPROLIFERATIVE DISORDER
The ability to release mature granulocyte to the blood
Myelokathexis
The absence of intermediate maturing cells between blast and mature neutrophil commonly seen in acute leukemia and myelodysplactic syndromes is called
Leukemic Hiatus
Increase levels of TdT are indicative of
ACUTE LYMPHOCYTIC LEUKEMIA
Increase leukocytes of all inaudibleassociated as a result of viral or bacterial infection
Leukocytosis
Process of basopenia includes all of the following except –
ANOREXIA NERVOSA
Barr bodies is only found in males
False
Ballerina skirt appearance
Downey Cells
Leukocytes that have been damaged during the preparation of peripheral blood
Smudge Cells
Has the appearance of blebs, vacuoles or pseudopods
Monocyte
Remnants of free ribosomes of RER
Dohle Bodies
All are true about basophil except
Survive for few days (hours rani sila mu survive)
Nucleated cells that do not containhemoglobin
WBC
Which inclusions can be seen leukocyte
Dohle Bodies
The neutrophil inaudible disease is capable producing
All of the above
Defined as an absolute decrease in thenumber of circulating neutrophils
Neutropenia
If your buffer is too acidic, RBC would be too
Pink
A falsely elevated hematocrit is obtained. Which of the following calculated values would not be affected
MCH (Formula: hemoglobin divided by RBC count x 10, no hematocrit. So,siya ra dli maapektuhan if nayproblem sa hematocrit kay hemglobin ra’y gipangita)
Increased RDW is correlated with
Anisocytosis
Which of the following statistical terms reflects the best index of precision when comparing two CBC parameters
COEFFICIENT OF VARIATION
A disorder caused by depressed chemotaxis and delayed degranulation
CHÉDIAK-HIGASHI SYNDROME
Sprawling nucleus
Monocyte
Role of eosinophils
SECRETE THE CONTENTS OF THEIR GRANULES
Plasma differs from serum that they contain
Factor 8
Which of the following protein is not present in the serum kay nagamit na siya
Fibrinogen
True or False: Normal serum contains platelets
False
Basophils are stimulated by
IgE
True or False: Normal blood is bacteriologically sterile
TRUE
A 0.85% solution of sodium chloride is known as
Saline Solution
An increase in eosinophils is seen in
All of the Above
How long does the monocyte circulate in the peripheral blood before becoming a tissue macrophage
3-72 hours
Which of the following test would not be included in a routine CBC
Reticulocyte
The peripheral white blood cells that aremore efficient at phagocytosis
Neutrophils
A blood pressure pumps is needed to carry out the following test
Ivy Test
In what way, Kuppfler cell, osteoclast, Alveolar macrophages, Langerhans cells similar
ALL FORMS OF TISSUE MACROPHAGES
True or False: platelet counts can be obtained by a capillary blood
False
If you have inaudible blood smear which should be prepare from whole blood which is good for few hours just as this satisfactory for differential counting and blood smears prepare from fresh blood provided that the specimen was kept in the refrigerator and it was thoroughly mixed just before the smear was made
False
True or False: Tourniquet should not be released until after the needle is out of the vein
False
Which of the following test does not require the preparation of the blood smear
Sedimentation Rate
Major adult hemoglobin
Alpha & Beta
Microcytic hypochromic red cells are associated in impaired
Hemoglobin
Which of the following is not characteristic of aplastic anemia
EXTRAMEDULLARY HEMATOPOIESIS
Variation in red cell sizes
Anisocytosis
Prepared cell for bone marrow aspiration
ILIAC Crest
Prepared cell for bone marrow aspiration
ILIAC Crest
Changes in shape of erythrocyte
Poikilocytosis
