HEMA MTAP RETAKE Flashcards

1
Q

Lazy Leukocyte syndrome

A

NEUTROPHIL

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2
Q

Variation in erythrocyte size

A

Anisocytosis

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3
Q

Variation in erythrocyte shape

A

Poikilocytosis

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4
Q

Average diameter of a normal RBC

A

7.2

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5
Q

Four stages (maturation sequence) for thrombocyte

A

Megakaryoblast
Promegakaryocyte
Megakaryocyte
Thrombocyte

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6
Q

as a blood cell matures, the N:C ratio?

A

Decrease

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7
Q

If a child ingested rat poison, test is for:

A

Prothrombin Time
“Prothrombin is a protein produced by the liver that helps blood to clot. Rat poisons, particularly those containing warfarin or similar substances, work by interfering with vitamin K and inhibiting the production of clotting factors, which can lead to bleeding issues.”

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8
Q

Megaloblastic Anemia: size, color

A

Macrocytic, Normochromic

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9
Q

A patient with a severe decrease in factor X activity would demonstrate normal:

A

Bleeding Time

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10
Q

If a blood smear is too long:

A

INCREASE THE ANGLE OF THE PUSHER SLIDE

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11
Q

Normal range for reticulocyte:

A

0.5-2.0

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12
Q

For maturation sequence of new segmented neutrophil, what is the first sequence?

A

Myeloblast

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13
Q

Increased amount of 2,3 DPG

A

Decrease oxygen affinity

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14
Q

von willebrand disease affected which test

A

Bleeding Time

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15
Q

Therapeutic Range for APTT

A

60-100

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16
Q

Which factor is a Labile factor

A

Factor V

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17
Q

Which parameters are calculated rather than directly measured in CBC:

A

HEMATOCRIT AND RDW (erythrocyte distribution width)

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18
Q

Vitamin K dependent factors:

A

The prothrombin group factors II, VII, IX, and X are called vitamin K-dependent factors.

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19
Q

Which maturation sequence in segmenters is Azurophilic/Primary/Non-specific granules:

A

Promyelocyte

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20
Q

Acantocytes:

A

ABETALIPOPROTEINEMIA

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21
Q

Normal color of neutrophil cytoplasm:

A

Tan or PINK

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22
Q

Operational body iron is normally contained:

A

Hemoglobin

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23
Q

The reagent used in the traditional sickle cell screening test is:

A

Sodiumdithionide

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24
Q

Microspherocytes are found in:

A

Hemolytic Disease or Newborn

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25
Q

Folded Membrane

A

Washington Disease

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26
Q

Stain that stains more crystal violet?

A

Methylene Blue

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27
Q

Acquired platelet Disorder

A

UREMIA

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28
Q

Lysosomal storage disease characterized by macrophages striated cytoplasm with store problem in the storage of glucocerebrosidase:

A

Gaucher’s Disease

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29
Q

If you are grading changes in erythrocytic size or shape using a scale of 0 to 4+ and many erythrocytes deviate from normal per microscopic field, the typical score would be:

A

3+

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30
Q

Myeloid and monocytic-myelocytic:

A

Fab M4

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31
Q

Overanticoagulation affects:

A

Hematocrit

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32
Q

Programmed cell death:

A

Apoptosis

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33
Q

How is platelet satellitism corrected:

A

REDRAW BLOOD SAMPLE IN A BLUE TOP (CITRATE) TUBE INSTEAD OF EDTA

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34
Q

CLP is associated with:

A

LEUKOCYTE

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35
Q

Decrease ESR:

A

POLYCYTHEMIA

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36
Q

This organ is the site of sequestration:

A

SPLEEN

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37
Q

Which of the following morphologic changes occurs during normal blood cell maturation:

A

CONDENSATION OF NUCLEAR CHROMATIN

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38
Q

First CD marker/s to appear during the first stage of T-cell development:

A

CD2

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39
Q

Increase in RDW and MCV:

A

Megaloblastic Anemia

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40
Q

an erythrocyte histogram, the erythrocytes that are larger than normal will be to the _____ of the normal distribution curve

A

RIGHT

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41
Q

Once sufficient blood has been collected, when does the tourniquet will be withdrawn:

A

Before withdrawing the needle

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42
Q

Acute Myelomonocytic leukemia is FAB:

A

M4

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43
Q

Used for the diagnosis of FAB M6:

A

Periodic Acid-Schiff

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44
Q

Auer rods are characterized as:

A

Fused Primary Granules

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45
Q

Niemann-Pick:

A

Macrophages

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46
Q

Hairy cell leukemia:

A

TARTIC PERSISTANT ACID PHOSPHATASE

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47
Q

Major aggregation of blow cell cytometry:

A

UTILIZES MONOCLONAL ANTIBODIES

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48
Q

Hemoglobin electrophoresis, muuban ug migrate si C ug A2:

A

SN, F, N, A

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49
Q

Compute first the WBC count:

A

250

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50
Q

Which of the following is not true in terms of platelet characteristic:

A

all of them are true except letter D – because they are normally found circulating in their active form

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51
Q

Compute first the WBC count ayha ang corrected WBC count:

A

9,600

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52
Q

Excessive rouleux is correlated with increase in:

A

ESR

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53
Q

Expected lifespan of an RBC, how many months is the 120 days:

A

3-4 months

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54
Q

If a newborn has a hemoglobin H it would demonstrate 30% of:

A

FETAL

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55
Q

Compute for the MCV, MCHC:

A

Microcytic, Hypochromic

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56
Q

68 cells counted x 1000

A

68,000

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57
Q

Morphological characteristic associated with Chediak-Higashi:

A

GIANT LYSOSOMAL GRANULES

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58
Q

Rule of three: multiply si hemoglobin by three:

A

Hematocrit

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59
Q

Precursor for neutrophil

A

BAND

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60
Q

Massive automated blood cell counter is based on:

A

Impedance principle

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61
Q

All of the following are true in iron deficiency anemia except:

A

Decrease in RBC

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62
Q

Platelet precursor:

A

Megakaryocyte

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63
Q

Aspirin affects:

A

Inhibition of cyclooxygenase

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64
Q

Accept or Reject: Clotted specimen for hematology

A

Reject

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65
Q

Which of the following method is not used to detect in differentiating WBCs: *how do you determine you WBC?

A

Through conductivity of measurement using the choice A, B and C except letter D – for HgB

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66
Q

How do compute for MCV?

A

HCT DIVIDED BY RBC MULTIPLY BY 100.

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67
Q

Why do we view specimen under the 10x objective:

A

All of the Above

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68
Q

Warm bodies:

A

NAD

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69
Q

Which organ do T-lymphocytes matures

A

Thymus

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70
Q

Corrected WBC count

A

9,800

71
Q

Bone Marrow aspirate is >90% blasts:

A

ACUTE LEUKEMIA

72
Q

Lipemic sample *which is affected?

A

Ang nay HgB: MCHC

73
Q

Prominent morphologic feature of lead poisoning:

A

Basophilic Stippling

74
Q

Beta is chromosome:

A

11

75
Q

Which of the following is not a function of Tlymphocyte:

A

SYNTHESIZE ANTIBODY

76
Q

Clotted sample and which one is most affected:

A

Platelet Count

77
Q

Auto-agglutination of red cell at room temperature can dissolve in which of the following:

A

ALL OF THESE – it will result in low RBC count, high MCV, low HCT

78
Q

Sickle cell anemia, valine is substituted as glutamic acid at the sixth position on the ___ chain of the hemoglobin molecule:

A

BETA

79
Q

BITE CELLS:

A

G6PD

80
Q

DIC is associated with:

A

ACUTE PROMYELOCYTIC LEUKEMIA (FAB M3)

81
Q

Polycythemia vera is characterized as an absolute decrease in:

A

Total Red Cell Mass

82
Q

If naa’y Philadelphia chromosome, prognosis is?

A

BETTER

83
Q

Which of the following is not associated with a causing falsely low ESR:

A

Column is Slanted

84
Q

What combination of reagent is used to measure hemoglobin:

A

POTASSIUM FERRICYANIDE AND POTASSIUM CYANIDE

85
Q

What are the reason RBCs are so bright red:

A

ACIDIC

86
Q

LAP Score:

A

Polycythemia Vera

87
Q

Principle of impedance:

A

AMPLIFICATION OF ELECTRICAL CURRENT OF BLOOD CELLS

88
Q

To evaluate normal platelet numbers

A

8-20 platelet per fields

89
Q

after applying the tourniquet –

A

FALSELY ELEVATED HEMOGLOBIN (would occur if tourniquet is more than one minute –Hemoconcentration)

90
Q

Most preferred site for bone marrow aspiration biopsy for adult

A

ILIAC CREST (Superior Iliac Crest)

91
Q

For capillary collection for newborns, which of the following lancet should be used to avoid penetrating the bone –

A

1.75 mm

92
Q

Which of the following needs to be collected in a lavender top tube

A

CBC

93
Q

A phlebotomy is preparing her collection basket on June 14. Expiration of the tube is on June 2007. Can she use the tubes?

A

YES, THE TUBE EXPIRES ON THE LAST DAY OF THE MONTH

94
Q

If the blood is drawn quickly from the vein, the vein will have tendency to

A

Collapse

95
Q

All of the following are universal precautions except

A

PRECAUTION LABELS ARE IN ANY PATIENT SPECIMEN

96
Q

Order of draw for skin puncture blood specimen –

A

ALWAYS START WITH A SMEAR > EDTA > SERUM

97
Q

Five-part differential

A

NEUTROPHIL enumerate the three granulocyte, LYMPHOCYTE AND MONOCYTE

98
Q

Shift to the right

A

– 1, 2 and 3 (BODY TEMPETURE INCREASE, 2,3 DPG AND CO2 (opposite si pH)

99
Q

Microcytic red blood cell are seen in

A

All of the Above

100
Q

Macrocytic red blood cell are seen in following except

A

HEMOLYTIC ANEMIA(RBC in HA: normochromic, normocytic)

101
Q

Conditions wherein rouleux formation is seen

A

ALL

102
Q

Which of the following characterizes a bronze cell –

A

Increase MCHC

103
Q

What do you call the remnants of chromatin found in severe anemia (SA) –

A

Howell JOLLY BODIES

104
Q

Most valuable and reliable criterion for identifying mature and immature WBC

A

Nuclear Characteristic

105
Q

Primary granules containing micro peroxidase firs appear in what myelocytic stage

A

Promyelocyte

106
Q

In what stage do neutrophilic granules appear

A

Myelocyte

107
Q

An important marker associated with T-lymphocyte

A

CD2 and CD3; bsta T-lymphocyte single digit gyd na sya

✓ CD19 – B cell
✓ CD34 & 45 – Hematopoietic stem cells and 45 specific for WBC
✓ CD56 – NK Cells
✓ Lymphocyte – T cells

108
Q

Cell producing antibodies

A

Plasma Cell

109
Q

Cells in acute inflammation

A

Neutrophils

110
Q

80μm in size in a cell transit in chronic inflammation –

A

Mature Macrophage

111
Q

Parasitic infection and allergies

A

Eosinophils

112
Q

Diffused primary granules seen in myeloblast

A

Auer ROds

113
Q

Cell lineage associated with endomitosis

A

Thrombocytes

114
Q

The number of inversions needed to properly mixed pseudocitrate with a blood specimen

A

3-4

115
Q

What combination of reagents is used to measure hemoglobin

A

POTASSIUM FERRYCYANIDE AND POTASSIUM CYANIDE

116
Q

The slowest moving hemoglobin on an alkaline electrophoresis at pH 8.6 is

A

A2, C, E and S

117
Q

Which of the following is not associated with causing a falsely low ESR

A

Column is Slanted

118
Q

To best preserve cellular morphology, differential smears from EDTA specimen should be made no more than how many hours after collection

A

5 hours

119
Q

The patient has PD, how do you correct this problem for your blood smear

A

INCREASE THE ANGLE OF THE SPREADER SLIDE

120
Q

Components of Wright stain

A

Methylene Blue & Eosin

121
Q

What is the depth of the hematocytometer

A

0.10

122
Q

Which of the following would not be the cause of falsely low high MCHC of 38.3 in an automated instrument

A

Hereditary Spherocytosis

123
Q

What is the principle of the automated impedance counters

A

AMPLIFICATION OF ELECTRICAL CURRENT BY CELLS

124
Q

Which of the following is not associated with the increase of inaudible and decrease surface area of volume ratio

A

Beta Thallasemia

125
Q

If you have a clotted EDTA, unsa ang pwede matest –

A

Hemoglobin Test

126
Q

Excessive centrifugation causes

A

Falsely low results

127
Q

Other name for hematocrit

A

Packed red blood cell volume

128
Q

Gaucher

A

1,2 AND 3 (chicken scratch, wrinkled tissue paper, onion skin-like)

129
Q

HAIRY CELL LEUKEMIA

A

LYMPHOPROLIFERATIVE DISORDER

130
Q

The ability to release mature granulocyte to the blood

A

Myelokathexis

131
Q

The absence of intermediate maturing cells between blast and mature neutrophil commonly seen in acute leukemia and myelodysplactic syndromes is called

A

Leukemic Hiatus

132
Q

Increase levels of TdT are indicative of

A

ACUTE LYMPHOCYTIC LEUKEMIA

133
Q

Increase leukocytes of all inaudibleassociated as a result of viral or bacterial infection

A

Leukocytosis

134
Q

Process of basopenia includes all of the following except –

A

ANOREXIA NERVOSA

135
Q

Barr bodies is only found in males

A

False

136
Q

Ballerina skirt appearance

A

Downey Cells

137
Q

Leukocytes that have been damaged during the preparation of peripheral blood

A

Smudge Cells

138
Q

Has the appearance of blebs, vacuoles or pseudopods

A

Monocyte

139
Q

Remnants of free ribosomes of RER

A

Dohle Bodies

140
Q

All are true about basophil except

A

Survive for few days (hours rani sila mu survive)

141
Q

Nucleated cells that do not containhemoglobin

A

WBC

142
Q

Which inclusions can be seen leukocyte

A

Dohle Bodies

143
Q

The neutrophil inaudible disease is capable producing

A

All of the above

144
Q

Defined as an absolute decrease in thenumber of circulating neutrophils

A

Neutropenia

145
Q

If your buffer is too acidic, RBC would be too

A

Pink

146
Q

A falsely elevated hematocrit is obtained. Which of the following calculated values would not be affected

A

MCH (Formula: hemoglobin divided by RBC count x 10, no hematocrit. So,siya ra dli maapektuhan if nayproblem sa hematocrit kay hemglobin ra’y gipangita)

147
Q

Increased RDW is correlated with

A

Anisocytosis

148
Q

Which of the following statistical terms reflects the best index of precision when comparing two CBC parameters

A

COEFFICIENT OF VARIATION

149
Q

A disorder caused by depressed chemotaxis and delayed degranulation

A

CHÉDIAK-HIGASHI SYNDROME

150
Q

Sprawling nucleus

A

Monocyte

151
Q

Role of eosinophils

A

SECRETE THE CONTENTS OF THEIR GRANULES

152
Q

Plasma differs from serum that they contain

A

Factor 8

153
Q

Which of the following protein is not present in the serum kay nagamit na siya

A

Fibrinogen

154
Q

True or False: Normal serum contains platelets

A

False

155
Q

Basophils are stimulated by

A

IgE

156
Q

True or False: Normal blood is bacteriologically sterile

A

TRUE

157
Q

A 0.85% solution of sodium chloride is known as

A

Saline Solution

158
Q

An increase in eosinophils is seen in

A

All of the Above

159
Q

How long does the monocyte circulate in the peripheral blood before becoming a tissue macrophage

A

3-72 hours

160
Q

Which of the following test would not be included in a routine CBC

A

Reticulocyte

161
Q

The peripheral white blood cells that aremore efficient at phagocytosis

A

Neutrophils

162
Q

A blood pressure pumps is needed to carry out the following test

A

Ivy Test

163
Q

In what way, Kuppfler cell, osteoclast, Alveolar macrophages, Langerhans cells similar

A

ALL FORMS OF TISSUE MACROPHAGES

164
Q

True or False: platelet counts can be obtained by a capillary blood

A

False

165
Q

If you have inaudible blood smear which should be prepare from whole blood which is good for few hours just as this satisfactory for differential counting and blood smears prepare from fresh blood provided that the specimen was kept in the refrigerator and it was thoroughly mixed just before the smear was made

A

False

166
Q

True or False: Tourniquet should not be released until after the needle is out of the vein

A

False

167
Q

Which of the following test does not require the preparation of the blood smear

A

Sedimentation Rate

168
Q

Major adult hemoglobin

A

Alpha & Beta

169
Q

Microcytic hypochromic red cells are associated in impaired

A

Hemoglobin

170
Q

Which of the following is not characteristic of aplastic anemia

A

EXTRAMEDULLARY HEMATOPOIESIS

171
Q

Variation in red cell sizes

A

Anisocytosis

172
Q

Prepared cell for bone marrow aspiration

A

ILIAC Crest

173
Q

Prepared cell for bone marrow aspiration

A

ILIAC Crest

174
Q

Changes in shape of erythrocyte

A

Poikilocytosis