HEMA MRXUH Exam Flashcards
Which test is most useful for monitoring the therapeutic effect of warfarin?
A. Activated Partial Thromboplastin Time (aPTT)
B. Prothrombin Time (PT) with INR
C. Thrombin Time (TT)
D. Platelet count
B. Prothrombin Time (PT) with INR
What is the characteristic finding in a peripheral blood smear of a patient with aplastic anemia?
A. Hypersegmented neutrophils
C. Macrocytic red blood cells
B. Normocytic, normochromic red blood cells
D. Decreased number of all blood cell types
D. Decreased number of all blood cell types
Which of the following is the most common cause of a prolonged Prothrombin Time (PT) in a patient on anticoagulant therapy?
A.Vitamin K deficiency
C. Factor V Leiden mutation
B. Hemophilia A
D. Disseminated intravascular coagulation (DIC)
A.Vitamin K deficiency
What is a key feature of Hodgkin lymphoma when viewed under a microscope?
A. Reed-Sternberg cells
C. Monoclonal plasma cells
B. Atypical lymphoblasts
D. Smudge cells
A. Reed-Sternberg cells
Which of the following laboratory tests is most appropriate for monitoring patients on heparin therapy?
A. Prothrombin Time (PT)
B. Activated Partial Thromboplastin Time (aPTT)
C. International Normalized Ratio (INR)
D. Platelet count
B. Activated Partial Thromboplastin Time (aPTT)
Which of the following is a classic clinical feature of a patient with aplastic anemia?
A. Elevated white blood cell count
C. Hypercellular bone marrow
B. Pancytopenia
D. Hyperuricemia
B. Pancytopenia
Which laboratory finding is typically elevated in patients with chronic kidney disease and anemia?
A. Serum iron
C. Erythropoietin
B. Total iron-binding capacity (TIBC)
D. Serum ferritin
D. Serum ferritin
Which of these following hematological tests serves as a liver function test?
A. Prothrombin Time (PT)
C. Complete Blood Count
B. ABO Rh Typing
D. Reticulocyte Count
A. Prothrombin Time (PT)
Which test is used to assess the function of the intrinsic pathway of coagulation?
A. Prothrombin Time (PT)-venn
B. Activated Partial Thromboplastin Time (aPTT)
C. Thrombin Time (TT)
D. Platelet aggregation test
B. Activated Partial Thromboplastin Time (aPTT)
Which of the following conditions is associated with an increased risk of bleeding due to decreased platelet function rather than decreased platelet number?
A. Thrombocytopenic purpura
B. Liver Cirrhosis
C. Von Willebrand disease
D. Iron-deficiency anemia
C. Von Willebrand disease
Which laboratory finding is characteristic of disseminated intravascular coagulation (DIC)? diner
A. Decreased prothrombin time (PT)
C. Increased fibrin degradation products (D-dimer)
B. Elevated platelet count
D. Increased mean corpuscular volume (MCV)
C. Increased fibrin degradation products (D-dimer)
Which of the following is the primary defect in hemophilia A?
A. Deficiency of factor IX
C. Deficiency of factor XI
B. Deficiency of factor VIII
D. Deficiency of factor V
B. Deficiency of factor VIII
Which type of anemia is characterized by the presence of basophilic stippling of red blood cells?
A. Dead poisoning
C. Iron Deficiency Anemia
B. Sickle cell anemia
D. Folate deficiency
A. Dead poisoning
Which of the following is the most common cause of a low platelet count (thrombocytopenia)?
A. Immune thrombocytopenic purpura (ITP)
C. Vitamin K deficiency
B. Polycythemia vera
D. Hemolytic uremic syndrome (HUS)
A. Immune thrombocytopenic purpura (ITP)
In a patient with a high reticulocyte count, what is the most likely underlying issue?
A. Chronic kidney disease
B. Hemolytic anemia
C. Vitamin B12 deficiency
D. Chronic inflammation
B. Hemolytic anemia
Which of the following conditions is associated with an increased risk of thrombosis?
A. Hemophilia
C. Polycythemia vera
B. Thalassemia
D. Aplastic anemia
C. Polycythemia vera
Hemoglobin forms that are incapable of oxygen transport include
A. Deoxyhemoglobin and oxyhemoglobin
B. Oxyhemoglobin and carboxyhemoglobin
C.Carboxyhemoglobin and methemoglobin
D. Methemoglobin and deoxyhemoglobin
C.Carboxyhemoglobin and methemoglobin
An excessive accumulation of iron in body tissues is called?
A. Hemochromatosis
B. Erythroblastosis
C. Megaloblastosis
D. Acrocyanosis
A. Hemochromatosis
The coagulation factors referred to as “vitamin K-dependent” are
A. I, V, VIII, XIII
B. II, V, IX, XII
C. II, VII, IX, X
D. XI, XII, Fletcher, Fitzgerald
C. II, VII, IX, X
For patients with polycythemia, the ESR result would be?
A. Increased
B. Decreased
B. Decreased
For patients with anemia, the ESR result would be?
A. Increased
B. Decreased
A. Increased
Which of the following is NOT synthesized in the liver?
A. Factor VIII
B. Plasminogen
C. Protein C
D. von Willebrand factor
D. von Willebrand factor
The red cells observed on a peripheral blood smear show extreme anisocytosis with equal number of macrocytes and microcytes. Which of the following values correlate with this finding?
A. MCV 108.OfL, RDW 14.0%
C. MCV 75.0fL, RDW 16%
B. MCV 90.0fL, RDW 25.0%
D. MCV 88.0fL, RDW 12%
B. MCV 90.0fL, RDW 25.0%
If the angle of the smear is TOO HIGH, the smear is
A. Thinner
B. Thicker
B. Thicker
Which of the following is the primary function of red blood cells (RBCs)?
A. Oxygen transport
C. Blood clotting
B. Immune response
D. Nutrient transport
A. Oxygen transport
ENUMERATE THE REAGENTS/STAINS USED FOR PERIPHERAL BLOOD STAINING.
10% Buffered Formalin
Methylene Blue
Eosin
Ethanol/Alcohol
Which of the following conditions is associated with an increased risk of bleeding due to decreased platelet function rather than decreased platelet number?
A Thrombocytopenic purpura
C. Von Willebrand disease
B. Liver Cirrhosis
D. Iron-deficiency anemia
C. Von Willebrand disease
Which of the following laboratory tests is most appropriate for monitoring patients on heparin therapy?
A. Prothrombin Time (PT)
C. International Normalized Ratio (INR)
B. Activated Partial Thromboplastin Time (aPTT)
D. Platelet count
B. Activated Partial Thromboplastin Time (aPTT)
What is a key feature of Hodgkin lymphoma when viewed under a microscope?
A. Reed-Sternberg cells
C. Monoclonal plasma cells
B. Atypical lymphoblasts
D. Smudge cells
A. Reed-Sternberg cells
The coagulation factors referred to as “vitamin K-dependent” are
A. X. I, V, VIII, XIII
B. II, V, IX, XII
C. II, VII, IX, X
D. XI, XII, Fletcher, Fitzgerald
C. II, VII, IX, X
Hemoglobin forms that are incapable of oxygen transport include
A. Deoxyhemoglobin and oxyhemoglobin
B. Oxyhemoglobin and carboxyhemoglobin
C. Carboxyhemoglobin and methemoglobin
D. Methemoglobin and deoxyhemoglobin
C. Carboxyhemoglobin and methemoglobin
Which of the following is NOT synthesized in the liver?
A. Factor VIII
B. Plasminogen
C. Protein C
D. von Willebrand factor
D. von Willebrand factor
Which type of anemia is characterized by the presence of basophilic stippling of red blood cells?
A Lead poisoning
C. Iron Deficiency Anemia
B. Sickle cell anemia
D. Folate deficiency
A Lead poisoning
The red cells observed on a peripheral blood smear show extreme anisocytosis with equal number of macrocytes and microcytes. Which of the following values correlate with this finding?
A. MCV 108.0fL, RDW 14.0%
B. MCV 90.0fL, RDW 25.0%
C. MCV 75.0fL, RDW 16%
D. MCV 88.0fL, RDW 12%
B. MCV 90.0fL, RDW 25.0%
What is a congenital qualitative platelet disorder?
A. Senile purpura
B. Ehlers-Danos syndrome
C. Henoch-Schonlein purpura
D. Waldenstrom macroglobulinemia
B. Ehlers-Danos syndrome
Aspirin ingestion blocks the synthesis of:
A. Thromboxane A2
B. lonized calcium
C. Collagen
D. ADP
A. Thromboxane A2
The clinical presentation of platelet related bleeding may include all of the ff except:
A. Bruising
B. Nosebleeds
C. Gastrointestinal bleeding
D. Bleeding into the joints (hemarthroses)
D. Bleeding into the joints (hemarthroses)
What test may be used to confirm the presence of Lupus Anticoagulant?
A. Bestheda titer
B. PT
C. Antinuclear antibody
D. PTT using high-phospholipid reagent
D. PTT using high-phospholipid reagent
What is the most important application of the quantitative D-dimer test?
A. Diagnose primary fibrinolysis
B. Diagnose liver and renal disease
C. Rule out deep venous thrombosis
D. Diagnose AMI
C. Rule out deep venous thrombosis
Which of the following lysosomal storage diseases is characterized by macrophages with striated cytoplasm and storage of glucocerebroside?
A. Sanfilippo syndrome
B. Gaucher disease
C. Fabry disease
D. Niemann-Pick disease
B. Gaucher disease
Megaloblastic episodes in SCD can be prevented by prophylactic administration of:
A. Iron
B. Folic acid
C. Steroids
D. Erythropoietin
B. Folic acid
Patient’s with SCD usually do not exhibit symptoms until 6 months of age because:
A. The mother’s blood has a protective effect
B. Hemoglobin levels are higher in infants at birth
C. Higher levels of Hb F are present
D. The immune system is not fully developed
C. Higher levels of Hb F are present
Which of the following tests provides a good indication of accelerated erythropoiesis?
A. Urine Urobilinogen
B. Hemosiderin level
C. Reticulocyte count
D. Glycated hemoglobin level
C. Reticulocyte count
Which of the following is consistent with a diagnosis of Megaloblastic anemia?
A. Hyposegmentation of neutrophils
B. Decreased serum LDH level
C. Absolute increase in reticulocytes
D. Increased MCV
A. Hyposegmentation of neutrophils
An increased MCV, along with a high RDW suggests:
A. Iron Deficiency Anemia
B. Vit. B12 or Folate Deficiency
C. Sickle Cell Anemia
D. Normal blood picture
B. Vit. B12 or Folate Deficiency
What is the largest hematopoietic cell found in a normal bone aspirate?
A. Osteoblast
B. Myeloblast
C. Pronormoblast
D. Megakaryocyte
A. Osteoblast
Which of the following blood film findings indicates EDTA-induced pseudothrombocytopenia?
A. The platelets are pushed to the feathered edge
B.The platelets are adhering to WBCS
C. No platelets at all are seen on the film
D. The slide has a bluish discoloration
B.The platelets are adhering to WBCS
Factor: 1
Name:
Pathway:
Factor: 1
Name: Fibrinogen
Pathway: Common
Factor: 2
Name:
Pathway:
Factor: 2
Name: Prothrombin
Pathway: Common
Factor: 3
Name:
Pathway:
Factor: 3
Name: Tissue Thromboplastin
Pathway: Extrinsic
Factor: 4
Name:
Pathway:
Factor: 4
Name: Calcium
Pathway: Common
Factor: V
Name:
Pathway:
Factor: 5
Name: Labile
Pathway: Common
Factor: 7
Name:
Pathway:
Factor: 7
Name: Serum-Prothrombin Conversion Factor
Pathway: Extrinsic
Factor: 8
Name:
Pathway:
Factor: 8
Name: Anti-hemophilic Factor A
Pathway: Intrinsic
Factor: 9
Name:
Pathway:
Factor: 9
Name: Plasma Thromboplastin Component
Pathway: Intrinsic
Factor: 10
Name:
Pathway:
Factor: 10
Name: Stuart-Prower
Pathway: Common
Factor: 11
Name:
Pathway:
Factor: 11
Name: Anti-hemophilic Factor C
Pathway: Intrinsic
Factor: 12
Name:
Pathway:
Factor: 12
Name: Glass Factor
Pathway: Intrinsic
Factor: 13
Name:
Pathway:
Factor: 13
Name: Laki-Lorand
Pathway: Common
