Heavy Menstrual Bleeding Flashcards

1
Q

What are the causes of HMB?

A
P = polyps
A = adenomyosis
L = leiomyoma/ fibroids 
M = malignancy and hyperplasia
C = coagulopathy e.g. Von Willebrand's disease, liver disease
O = ovarian dysfunction e.g. PCOS, hypothyroid, hyperprolactinaemia, anorexia
E = endometrial dysfunction e.g. endometriosis, PID
I = iatrogenic 
N = not yet classified
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2
Q

What is the definition of HMB?

A

Prolonged menses (>7days) or excessive bleeding (loss >80ml) occurring at regular intervals

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3
Q

How do polyps present?

A

Often asymptomatic, found on hysteroscopy

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4
Q

What is the Ix for adenomyosis?

A

U/S - increased echogenicity within myometrium, myometrial hypertrophy, dilated glands

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5
Q

What is the treatment for adenomyosis?

A

Do nothing
Hormonal - OCP, IUD to reduce flow
Hysterectomy

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6
Q

How might fibroids present?

A

Often asymptomatic

May present with pressure Sx, frequency

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7
Q

What are fibroids?

A

Benign fibromuscular tumours that increase SA of endometrium so more to bleed from

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8
Q

What are Cx of fibroids?

A

Subfertility

If on a stalk can tort and infarct

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9
Q

What is the treatment for fibroids?

A
Do nothing
Hormonal - OCP, IUD to reduce flow
Hysterscopic resection if submucous 
Myomectomy 
Hysterectomy
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10
Q

What types of malignancy may cause HMB and how are they found?

A

Endometrial cancer - dx on endometrial sampling

Cervical cancer - dx on PAP smear/ HPV testing or colposcopy

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11
Q

What types of coagulopathy may cause HMB?

A

Von Willebrand’s disease
Plt dysfunction disorder
Factor deficiencies: V, IX, X

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12
Q

What are some causes of ovulatory dysfunction?

A

Thyroid (hypo/hyper)
Pituitary/ adrenal disease
PCOS
Significant weight loss

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13
Q

What is the treatment for polpys?

A

Do nothing
Hormonal - OCP, IUD to reduce flow
Hysteroscopic polypectomy
Hysterectomy

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14
Q

What are some iatrogenic causes of HMB?

A

OCP
IUD
Chemotherapy
Anticoagulation

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15
Q

Other causes of HMB?

A

Endometritis

Pregnancy Cx- ectopic, miscarriage

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16
Q

What Ix would you do for HMB?

A

FBE
Fe studies
consider bHCG
+/- coags, plt function assay, VWF (in adolescents and others with a suggestive Hx or FHx of bleeding disorder)
+/- LH, FSH, estradiol, androgen screen, TFTs (in those with hirsutism, acne, obesity and irregular cycles)
TV U/S +/- saline sonohysterogram (polyps)
Pipelle endometrial sample is the first line for excluding endometrial carcinoma or hyperplasia but hysteroscopy D&C is gold standard

17
Q

Management options for HMB

A

Antifibrinolytics e.g. tranexamic acid
Prostaglandin inhibitors e.g. mefenamic acid (ponstan)
Hormonal: OCP, depot provera, IUD
Surgical: endometrial ablation + tubal ligation, myomectomy, polypectomy, hysterectomy