heart failure - beta-adrenoceptor blockers

Question 1

T/F Most patients with chronic heart failure respond favorably to certain β blockers

Answer 1

T

Question 2

T/F Full understanding of the beneficial action of β blockade is lacking

Answer 2

T

Question 3

Suggested mechanisms og beta blockers

Answer 3

• Attenuation of the adverse effects of high concentrations of catecholamines (including apoptosis)
• Up-regulation of β receptors
• Decreased heart rate
• Reduced remodeling through inhibition of the mitogenic activity of catecholamines