Heart and Vessels Flashcards
Heart forming details
- Mesoderm plus cardiac crescent
- Blood islands
- Heart tubes plus blood
- Pericardial cavity
- Dorsal Aorta
- Heart tube compartments/divisions
- Tube folding
- Electrical conduction
Week 3-5
heart and vessels
Pharyngeal arches contain what?
- mesoderm
- cartilage (to bone)
- nerve
- blood vessel
What’s the purpose of heart development?
- creation of mesoderm into primitive heart and vascular system
- establishment of vascular system
Heart development steps
1.) Primitive streak
2.) Mesodermal layer (trilaminar disc)
3.) Primary heart field (into lateral folds)
4.) 2 heart tubes
5.) fused heart
6.) Formation of valves, etc.
“Card” equals
heart
Heart forming details at week 3: Mesoderm and _________ heart progenitor cells travels through primitive streak toward the embryo’s _____ (day 16) and travel to _________ mesoderm
Primitive; head; splanchnic
Splanchnic mesoderm becomes what?
heart
Heart forming details at week 3: Mesoderm also forms the _______ ________, these form in the cariogenic region and ______ to become a “horseshoe-shaped” mesoderm area with 2 limbs, called the ________ ________ __ _______ _______
Blood Islands; FUSE; Primary Cardiac Field or Cardiac Crescent
Vasculogenesis
secondary cardiac field
- forms vessels that become the 2 Heart Tubes!
The _____ Ventricle and outflow comes from the medial cardiac crescent –> populates the pharynx before migrating to form the heart –> “secondary field” of cardiac precursor not part of early linear heart tube
Right
During Week 3-4 (Day 19), the lateral mesoderm splits into what?
Somatic and splanchnic layer
When the body folds are growing laterally and fuse at the ventral midline the Ectoderm ____ signals to splanchnic mesoderm and thus the limb’s blood island cells to organize/specialize/differentiate into 2 __________ _____ AND __________ _________
VEGF; endocardial tubes (mesoderm); Pericardial Cavities
VEGF
Vascular Endothelial Growth Factor
At day 21-22, Endoderm VEGF influences ________ mesoderm, forming 2 endocardial tubes BUT layered…
splanchnic; 1.) Angioblast 2.) Hemocytoblast
Angioblast
blood vessels –> heart tube –> endocardium
Hemocytoblast
blood cells precursor
Endocardial tubes ____ with body folding
FUSE
The embryonic coelom gives rise to what?
Primitive pericardial cavity
Primitive pericardial cavity forms ______ to each cardiac tube
lateral
Mesoderm cells also form a pair of longitudinal vessels called what?
dorsal aorta
Embryo is all _____ to _____ folding
cranial; caudal
- neural tube now formed
Layers of Heart Tube
1.) Endocardium
2.) Cardiac Jelly (secreted)
3.) Myocardium
At first, the heart tube and pericardial coelom are ________, BUT when head folds, it pushes heart (stuffs it) into the __________ cavity
Separate; pericardial
As the heart tube fuse, the primordial myocardium forms from ____________ mesoderm of the pericardial coelom
splanchnic
The epicardium (visceral pericardium) arise from the _______ surface of the sinus venous and spreads on the myocardium
external
The 2 heart tubes fused into 1; this tube will continue to ___________
differentiate
