Heart Flashcards

1
Q

Describe the size, shape, location and orientation of the heart in the thorax.

A

The heart is a muscular organ, roughly the size of a fist, located in the thoracic cavity between the lungs, tilted slightly to the left.

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2
Q

Name the coverings of the heart.

A

The heart is covered by the pericardium, which includes the fibrous pericardium and the serous pericardium.

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3
Q

Describe the structure and function of each of the three layers of the heart wall.

A

The three layers are:
* Epicardium: outer layer providing protection
* Myocardium: middle layer responsible for contraction
* Endocardium: inner layer lining the chambers and valves.

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4
Q

Describe the structure and functions of the four heart chambers.

A

The four chambers are:
* Right atrium: receives deoxygenated blood from the body
* Right ventricle: pumps deoxygenated blood to the lungs
* Left atrium: receives oxygenated blood from the lungs
* Left ventricle: pumps oxygenated blood to the body.

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5
Q

Name the great vessels associated with each heart chamber.

A

Associated vessels are:
* Right atrium: superior and inferior vena cava
* Right ventricle: pulmonary arteries
* Left atrium: pulmonary veins
* Left ventricle: aorta.

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6
Q

Trace the pathway of blood through the heart.

A

Blood flows from the body into the right atrium, then to the right ventricle, to the lungs via pulmonary arteries, back to the left atrium, to the left ventricle, and out to the body through the aorta.

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7
Q

Name the major branches of the coronary arteries.

A

Major branches include:
* Left coronary artery
* Right coronary artery.

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8
Q

Describe the distribution of the coronary arteries.

A

The left coronary artery supplies the left side of the heart, while the right coronary artery supplies the right side.

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9
Q

Name the heart valves.

A

The heart valves include:
* Tricuspid valve
* Pulmonary valve
* Mitral valve
* Aortic valve.

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10
Q

Describe the location and function of the heart valves.

A

Valves are located between:
* Right atrium and right ventricle (tricuspid)
* Right ventricle and pulmonary artery (pulmonary)
* Left atrium and left ventricle (mitral)
* Left ventricle and aorta (aortic).
Function: prevent backflow of blood.

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11
Q

What is the mechanism of operation of the heart valves?

A

Valves open and close based on pressure changes in the heart chambers.

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12
Q

Describe the structural and functional properties of cardiac muscle.

A

Cardiac muscle is striated, involuntary, and has intercalated discs for synchronized contraction.

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13
Q

How does cardiac muscle differ from skeletal muscle?

A

Cardiac muscle is involuntary and branched, while skeletal muscle is voluntary and multinucleated.

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14
Q

Briefly describe the events of cardiac muscle cell contraction.

A

Contraction is initiated by an action potential, leading to calcium ion release, which triggers muscle fiber shortening.

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15
Q

Name the components of the conduction system of the heart.

A

Components include:
* Sinoatrial (SA) node
* Atrioventricular (AV) node
* Bundle of His
* Purkinje fibers.

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16
Q

Trace the conduction pathway of the heart.

A

The conduction pathway is: SA node → AV node → Bundle of His → Purkinje fibers.

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17
Q

Draw a diagram of a normal electrocardiogram tracing; name the individual waves.

A

Waves include:
* P wave: atrial depolarization
* QRS complex: ventricular depolarization
* T wave: ventricular repolarization.

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18
Q

What abnormalities can be detected on an ECG tracing?

A

Abnormalities include arrhythmias, ischemia, and hypertrophy.

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19
Q

Describe the timing and events of the cardiac cycle.

A

The cardiac cycle includes:
* Atrial systole
* Ventricular systole
* Diastole.

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20
Q

Describe normal heart sounds.

A

Normal heart sounds include ‘lub’ (closure of AV valves) and ‘dub’ (closure of semilunar valves).

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21
Q

How do heart murmurs differ from normal heart sounds?

A

Murmurs are abnormal sounds due to turbulent blood flow.

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22
Q

Name factors regulating stroke volume and heart rate.

A

Factors include:
* Preload
* Afterload
* Contractility
* Autonomic nervous system.

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23
Q

Explain the role of the autonomic nervous system in regulating cardiac output.

A

The autonomic nervous system adjusts heart rate and contractility through sympathetic and parasympathetic stimulation.

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24
Q

Provide examples of age-related changes in heart function.

A

Examples include decreased maximum heart rate, increased stiffness of the heart muscle, and changes in electrical conduction.

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25
What is the approximate size and weight of the heart?
About the size of a fist, weighs less than one pound
26
Where is the heart located?
Enclosed in the mediastinum, resting on the diaphragm between the vertebral column and sternum
27
What are the three functions of the fibrous pericardium?
* Protection * Anchoring * Prevents overfilling
28
What are the two layers of the serous pericardium?
* Parietal layer * Visceral pericardium (epicardium)
29
What is the pericardial cavity?
Fluid-filled space between serous and visceral layers containing slippery serous fluid
30
What is pericarditis?
Inflammation of the pericardium resulting in pericardial friction rub
31
What is pericardial tamponade?
Excessive pressure on heart due to overfilling of the pericardium with blood or fluid
32
What are the three layers of the heart wall?
* Epicardium * Myocardium * Endocardium
33
What is the role of the myocardium?
It is the bulk of the heart responsible for contraction
34
What are the four chambers of the heart?
* 2 Atria * 2 Ventricles
35
What separates the two atria?
Interatrial septum
36
What separates the ventricles?
Interventricular septum
37
What is the atrioventricular groove?
Groove marking the boundary between atria and ventricles, also called coronary sulcus
38
What is the function of auricles?
Minimally increase atrial volume
39
What are pectinate muscles?
Muscles in the anterior portion of the atria with a 'raked' appearance
40
What is the function of the fossa ovalis?
Thin area of interatrial septum where foramen ovale existed in fetal heart
41
What are the three vessels returning blood to the right atrium?
* Superior Vena Cava * Inferior Vena Cava * Coronary sinus
42
What are trabeculae carneae?
Ridges of muscle inside the ventricles
43
What are papillary muscles?
Muscles that support and anchor chordae tendineae
44
What prevents backflow from the aorta to the left ventricle?
Aortic semilunar valve
45
What prevents backflow from the pulmonary artery to the right ventricle?
Pulmonary semilunar valve
46
What is systemic circulation?
Oxygen-rich blood flow from the left side of the heart to the body
47
What is pulmonary circulation?
Blood flow to and from the lungs via the right side of the heart
48
What is coronary circulation?
Blood supply specifically for the heart
49
What is myocardial infarction?
Prolonged blockage of coronary arteries causing myocardial cell death
50
What is angina pectoris?
Brief deficiency of oxygen to the heart
51
What are the three major cardiac veins?
* Great cardiac vein * Middle cardiac vein * Small cardiac vein
52
What are the shared characteristics between cardiac and skeletal muscle?
* Actin-myosin filament sliding model * A-bands, I-bands, Z-disc * Sarcolemma, Sarcoplasmic reticulum, T-tubules * Depolarization of muscle membranes
53
What characterizes the autorhythmic cells of the heart?
They have an unstable resting potential that continuously depolarizes
54
What is the function of the sinoatrial (SA) node?
Sets the pace for the entire heart by depolarizing about 75 times per minute
55
What is the role of the atrioventricular (AV) node?
Delays impulses for ~0.1 seconds allowing atria to contract
56
What is the function of Purkinje fibers?
Stimulate papillary muscles and ensure simultaneous contraction of ventricles
57
What is fibrillation?
Rapid and irregular contractions of the heart
58
What does electrocardiography monitor?
The electrical currents of the heart
59
What is the basic heart rate set by?
Intrinsic conductance system
60
Which system increases heart activity?
Sympathetic nervous system (norepinephrine)
61
Which system slows heart activity?
Parasympathetic nervous system (acetylcholine)
62
Define fibrillation.
Rapid and irregular or out-of-phase contractions
63
What is defibrillation?
Accomplished by electrical shock
64
What does the P wave represent in an ECG?
Depolarization of the atria
65
What does the QRS complex signify in an ECG?
Depolarization of the ventricles
66
What does the T wave indicate in an ECG?
Ventricular repolarization
67
What is heart block?
A problem with the heart where part of the normal impulse conductance system is non-functional
68
What happens in a first-degree AV block?
Impulse is delayed on way to AV node, lengthening the interval between P and R waves
69
What characterizes a second-degree AV block (type I)?
Progressive lengthening of the P-R interval until one impulse is not passed
70
What is tachycardia?
Too fast heart contractions
71
What is bradycardia?
Too slow heart contractions
72
Define systole.
Contraction of the heart chambers
73
Define diastole.
Relaxation of the heart chambers
74
What is the initial phase of the cardiac cycle?
Ventricular filling
75
What happens during isovolumetric contraction phase?
Both AV and semilunar valves are closed for a split second
76
What is end systolic volume (ESV)?
Volume of blood remaining after systole
77
What is cardiac output (CO)?
The amount of blood pumped by each ventricle in 1 minute
78
How is cardiac output calculated?
CO = HR X SV
79
What does stroke volume (SV) represent?
The amount of blood ejected from ventricle with each contraction
80
What is the Frank Starling law of the heart?
More blood in the chamber before contraction leads to greater stroke volume
81
What is preload?
The amount of blood in the chamber before it contracts
82
What is contractility?
The strength of cardiac contraction independent of preload
83
What can increase contractility?
* Ca++ * Glucagon * Thyroid hormone (TH) * Epinephrine
84
What can decrease contractility?
* Excessive H+ * Rising extracellular K+ * Calcium channel blockers
85
What is afterload?
Pressure in aorta and pulmonary trunk that can decrease amount of blood leaving ventricles
86
What sets the heart rate?
SA node
87
What effect does norepinephrine have on heart activity?
Stimulates cardiac activity
88
What effect does acetylcholine have on heart activity?
Inhibits cardiac activity
89
What does epinephrine do in relation to heart function?
Causes many of the same effects as norepinephrine release from sympathetic nervous system
90
What long-term effect does thyroxine have on heart rate?
Causes long-term increase in heart rate
91
innermost lining of heart is known as
endocardium
92
heart strings are called
chordae tendinaea
93
to ensure proper cardiac contraction, Ca must be allowed to flow from one cell to the next thru
gap junctions
94
what happens during QRS complex in typical EKG
Depolarize ventricles
95
how much blood pumped by adult heart in 1 min at normal sinus rhythm
5 liters
96
chest compartment holding heart, thymus, part of trachea and esophagus...
mediastinum
97
mitral and bicuspid valve is the
left AV valve
98
autodepolarization of heart begins at
SA node
99
Normal blood pressure
120 systolic 80 diastolic
100
hypertension is pressure of
140 systolic 90 diastolic
101
vascular tunica intima is composed of what cell?
endothelial
102
type of capillaries in blood brain barrier?
continuous
103
short term regulation of BP?
vasoconstriction or dilation of muscular arteries
104
which of the following would not be expected result of increased Renin?
increased urine output
105
where in circulatory system does blood move slowest?
capillaries
106
Vessels that exit the heart
aorta Pulmonary trunk and arteries
107
Vessels that return to the heart
Pulmonary veins Coronary sinus SVC IVC
108
Difference features in cardiac muscle from skeletal
Functional syncytium, gap junctions, desmosomes, Intercalated disks
109
Papillary muscle is where in the heart
supporting Chordae tendinae
110
Interventricular system is
between the ventricles
111
Pulmonary trunk/artery is where
into RV
112