heart Flashcards
RBC func and adapt
Function of RBC: contains haemoglobin for the transport of oxygen from lungs to all cells in body
Packs haemoglobin that binds reversibly to oxygen and allow oxygen to be transported from lungs to all parts of body
Circular, biconcave shape to increase surface area to volume ratio for faster rate of diffusion of oxygen in and out of the RBC
No nucleus so that the RBC can contain more haemoglobin so that more oxygen can be packed in RBC and more oxygen can be transported from lungs to around the body at a faster rate.
WBC func and types and shapes
Function: play a vital role in keeping the body healthy by fighting pathogens
Phagocytes: engulf, ingest and digests the bacteria ( has an lobed shape nucleus )- phagocytosis where phagocytes engulf the pathogens
Lymphocytes: produces antibodies ( has large nucleus ) - Producing antibodies
Has nucleus
Can change its shape to squeeze through walls of blood capillaries to surrounding tissues
platelets func and blood clottign prcoess
Function: blood clotting
Not a cell
Membrane bound fargemnts of cytoplasm from bone marrow cells
When cut, damaged tissues and platelets produce thrombokinase. Prothromin which is inactive is converted into thrombin that is active by thrombokinase in the presence of calcium ions. Fibrinogen is converted to insoluble fibrin threads by thrombin. The fibrin threads from a mesh that traps blood cells, hence blood clotting takes place. The blood clot prevents excessive loss of blood and entry of pathogens into blood.
production of antibodies
When pathogens enter the bloodstream, the lymphocytes are stimulated to produce antibodies. The antibodies destroy the bacteria by attaching to them and clump them together during agglutination so that the phagocytes can ingest the bacteria more easily. The antibodies neutralize the toxins produced by bacteria
phagocytosis
The phagocytes engulf, ingest and digest the bacteria
The process of engulfing, ingestong and digesting pathogens by WBC
blood clotting
by platelets
Heparin is produced by liver and is an anti-clotting substance that is neutralised by thrombokinase
tissue rejection
When transplanted organ is treated as a foreign object by recipient’s immune system
The phagocytes attack organ and lyohocytes produce antibodies
To prevent: use immunosuppressive drugs / transplant tissue frm the same person / from relatives
blood groups, antigen and antibody
Grp A - antigen A and antibody b
Grp B - antigen B and antibody a
Grp O - no antigen and antibody a + b (universal donor)
Grp AB - Antigen A + B and no antibody (universal recipient)
blood transfusion
Donor antigen + recipient antibody (cannot be same letter, if not agglutination occurs)
Donor - RBC
Recipient - plasma
where is antigen and antibiyd found on?
Antibody found on plasma
Antigen found on RBC surface
function of blood
Protects the body against pathogens
Allows blood clotting tio take place to prevent excessive loss of blood
Acts as a transport medium to allow the transport 0f subs around the body
blood flow
Venules -> vein -> heart -> artery -> arterioles -> capillaries
function of artery and adaptation
Function: transports blood away from heart
Muscular, thick wall of artery - withstand the immense pressure of blood flowing thrugh the artery
Elastic tissues in wall of artery - stretch and recoil under high pressure and exerts more pressure on the wall of artery, hence blood is pumped with higher pressure and wall pushes blood more quickly along the artery in spurts
If the wall of artery is not thick, the wall will be unable to withstand the high blood pressure and will rupture
vein func and adaotation
Function: transports blood towards heart
Semi-lunar valves - to prevent backflow of blood, ensuring that blood only flows in one correct direction
Contraction and relaxation of skeletal muscles - generate more pressure so that blood flows at greater pressure
Large lumen - low resistance to blood flow so that there is a smooth blood flow
capillary func and adaptation
Function: allows for exchange of substances between body cells and blood + transports blood from arterioles to venules
One cell thick partially permeable wall which is made up of a single layer of endothelial cells which reduces the diffusion distance so that substances can diffuse in and out of capillary faster
Numerous branching of capillaries so that there is higher cross sectional area such that there is lower blood pressure and the blood flow is slower and there is more time for substances to diffuse in and out of capillary, hence more time for exchange of substances between blood and body cells
If the capillary wall is not thin, diffusion of substances across the capillary wall between tissue cells and blood will not pccur