Heamostasis

Question 1

NORMAL HAEMOSTASIS

Answer 1

Haemostasis requires the interaction of three compartments
• The blood vessels
• The platelets
• The coagulation factors (soluble plasma proteins)
Must be tightly controlled!!

Question 2

HAEMOSTASTIC MECHANISM

Answer 2

1)Haemostatic mechanism is three distinct phases:
• Primary haemostasis
• Interactions between blood vessels, platelets and vWF

2)Secondary haemostasis
•Pathways of coagulation to generate fibrin strands

3)Fibrinolysis
• Biochemicalsystemthatdegradesthefibrinclot

Question 3

• Primary haemostasis

Answer 3

Interactions between blood vessels, platelets and vWF

Question 4

Secondaryhaemostasis

Answer 4

Pathwaysofcoagulationtogeneratefibrin strands

Question 5

Fibrinolysis

Answer 5

Biochemical system that degrades the fibrin clot