Headaches Flashcards
What kind of onset may headaches have?
Acute
Subacute
Gradual
What kind of exacerbating factors may headaches have? Give examples.
Valsalva
e.g coughing, sneezing, straining
Headaches may have …….. variation
DIURNAL
Name some associated symptoms of headaches.
Photophobia, phonophobia, positive visual symptoms, ptosis, miosis, nasal stuffiness etc
Migraines tend to occur in…..
YOUNGER FEMALES
List the 5 red flags of headaches.
New onset in someone >55 Known/previous malignancy Immuno-suppressed Early morning headache Exacerbated by Valsalva
What should you be aware of in someone’s PMH?
Previous CA
Predisposition to thrombus
What should be asked about in FHx?
Migraines
What should you remember to ask about in drug history?
Over the counter medication
Headaches are more common in?
WOMEN
On average, how often do most people have an attack?
1 per month
What % experience migraine i) with aura ii) without aura?
i) 20%
ii) 80%
What is the HIS criteria for a migraine without aura?
- At least 5 attacks.
- Of duration 4-72hours.
+ - 2 of: moderate/severe, unilateral, throbbing pain, worse with movement.
- 1 of: autonomic features, photophobia/phonophobia
What 2 influences cause an individual to be susceptible to migraines?
Neural and vascular
Describe the pathophysiology of a migraine.
Stress triggers changes in the brain, and these changes cause SEROTONIN to be released.
Blood vessels constrict and dilate.
Chemicals including SUBSTANCE P irritate nerves and blood vessels, causing pain.
Aura is a …….
FULLY REVERSIBLE visual, sensory, motor or language symptom
What does aura duration tend to be?
20-60 minutes
When does a headache occur in relation to aura?
<1 hour but both can occur simultaneously
What type of aura is most common?
VISUAL
positive symptoms usually monochromatic
Suggest factors which may trigger a headache.
Sleep. Dietary – cheese, red wine. Stress. Hormonal – young females in early teens, or females in 40’s. Physical exertion.
What can be used to help identify triggers?
A headache diary
Suggest non-pharmacological methods of treating a migraine.
- Set realistic goals
- Education – avoid triggers
- Headache diary
- Relaxation/Stress management
Pharmacological treatment is either?
Acute or Prophylactic
Outline the acute management of a headache.
Aspirin 900mg
Naproxen 250mg
Ibuprofen 400mg
+ anti-emetic
What kind of drug are triptans?
5 HT agonist
When are triptans taken?
At the start of the headache
What should be considered when deciding the route of triptans?
If patient has nausea and vomiting then don’t give oral
When should prophylaxis for headaches be considered?
If person is having more than 3 attacks per month, or very severe attacks
How long should a prophylactic drug be trialled for?
At least 3 months
What non-pharmacological methods should be tested for prophylaxis?
Acupuncture
Relaxation exercises
Name 2 prophylactic drugs.
Propanolol
Topiramate
What does propranolol do?
Reduction in migraine frequency in around 60-80% of patients.
What is the range of suitable doses of propanolol?
80-240mg
When should propranolol be avoided?
Asthma and PVD (heart failure)
What type of drug is topiramate?
A carbonic anhydrase inhibitor
What range of doses can be given for topiramate?
25-100mg
What are the side effects of topiramate? What should you therefore do?
Weight loss. Paraesthesia. Impaired concentration. Enzyme inducer START LOW, GO SLOW
What are the side effects of amitriptyline?
Dry mouth, postural hypotension, sedation
What dietary advice should you give?
Ensure regular intake
Avoid triggers
Maintain a healthy balanced diet
In terms of hydration, what should you tell patients?
At least 2 litres per day
Decrease caffeine
For a typical migraine, what investigations are required?
NONE
When should imaging for a migraine be considered?
If late onset - > 55.
Known malignancy.
Acephalgic (ie. no headaches) migraine
Migraine is?
A common UNILATERAL headache of the young
Consider prophylaxis for those who have more than 3 attacks per month
TRUE
Tension headaches can be either …….. or ……?
Episodic
OR
Chronic
Describe the main features of a tension headache.
Pressing/Tingling quality
Mild to moderate
Bilateral
What features sometimes associated with headache are absent in a tension-type headache?
Nausea
Vomiting
Photophobia
Phonophobia
How are tension headaches managed?
- Relaxation physio
- Anti-depressant for 3 months - dothiepin or amitriptyline
- Reassurance is often enough
What are the Trigeminal Autonomic Cephalgias (TACs)?
A group of primary headache disorders, characterised by unilateral trigeminal distribution pain that occurs in association with prominent ipsilateral cranial autonomic features
What are ipsilateral cranial autonomic features?
Ptosis. Miosis. Nasal stuffiness. Nausea/vomiting. Tearing. Eye lid oedema
Name the 4 main types of TAC.
- Cluster.
- Paroxysmal hemicrania.
- Hemicrania continua.
- SUNCT
Who tends to get cluster headaches?
young 30’s - 40’s
men > women
When do cluster headaches occur?
- Striking circadian (around sleep).
* Seasonal variation.
Describe features of a cluster headache.
- Severe UNILATERAL headache.
unlike people with migraine, these people struggle to stay still.
What is the duration of cluster headaches?
45-90 minutes
What is the frequency of cluster headaches?
1 to 8 days
How long may cluster bouts last?
From a few weeks to months
Outline the treatment of cluster headaches.
- High flow oxygen, 100% for 20 mins.
- Subcutaneous sumatriptan 6mg.
- Steroids – begin at start of cluster, then reduce course over 2 weeks.
What is given as prophylaxis of cluster headaches?
Verapamil
Who gets paroxysmal hemicrania?
Elderly people – 50s-60s.
Women > men
Outline the features of paroxysmal hemicrania.
- SEVERE UNILATERAL headache, with UNILATERAL AUTONOMIC features
What is the duration of paroxysmal hemicrania headaches?
10-30 mins
What is the frequency of paroxysmal hemicrania headaches?
1-40 days
Paroxysmal hemicrania headaches are SHORTER in duration, and more FREQUENT than cluster
TRUE
What is the treatment of paroxysmal hemicrania/hemicrania continua?
ABSOLUTE response to INDOMETHICIN
Explain what SUNCT is.
S = Short lived (15-120secs). U = Unilateral. N = Neuralgiaform headache. C = Conjunctival injections. T = Tearing
What is SUNCT treated with?
Lamotrigine.
Gabapentin
When is investigations needed?
Those with new onset unilateral cranial autonomic features require imaging.
What imaging is done?
MRI brain
MR angiogram
Who is affected by IIH?
F>M
Obese people - almost never see people with normal BMI with this
Outline the features of IIH.
Headache that has diurnal variation.
Morning n + v.
Visual loss.
What investigations should be done for IIH? What are the expected results of each of these?
Fundoscopy.
* papilloedema, absence of venous pulsation
MRI brain with MRV sequence.
* normal
Lumbar Puncture.
* CSF – elevated pressure, normal constituents
Visual fields
These are the one group of pts where you can do a lumbar puncture even if they have papilloedema. First, ensure MRI is normal.
TRUE
How is IIH managed?
- Weight loss.
- Acetazolamide.
- Ventricular atrial/lumbar peritoneal shunt.
- Monitor visual fields and CSF pressure.
Who gets trigeminal neuralgia?
- Elderly people, >60y/o.
* Women > Men
What triggers trigeminal neuralgia?
Touch, usually in the CN V2/3 distribution
- Severe STABBING unilateral pain
TRIGEMINAL NEURALGIA
- What is the duration of trigeminal neuralgia?
1-90 seconds
What is the frequency of trigeminal neuralgia?
10-100 days
How long may bouts of pain last before remission in trigeminal neuralgia?
From a few weeks to months
What investigations are done for trigeminal neuralgia? Why?
MRI brain.
IF there are any signs on examination, atypical features, poor response to medical treatment or if surgical treatment is being considered
What drugs may be used in the medical tx of trigeminal neuralgia?
Carbamazepine.
Gabapentin.
Phenytoin.
Baclofen.
What are the 2 main surgical options in the treatment of trigeminal neuralgia?
Ablation
OR
Decompression