HEAD & NECK TUMOURS Flashcards
Region described from the ___________ to the _________________.
- excludes tumours of the ___________ contents and tumours of the ___________ and ___________
cranium ; base of the neck.
intracranial
globe and orbit
Head and neck tumors
Constitutes ____% of all cancers
Approx 500,000 cases diagnosed annually Approx. 300,000 deaths worldwide
Male : Female ___:____
3-5
2:1
Head and neck tumors Can be
- __________ , __________ or __________
- __________ and __________ tumours.
Can be
- benign, intermediate or malignant
- Epithelial and non-epithelial tumours.
Generally –
Benign:
*___________
* ___________
* ___________
* ___________
*Fibroma/angiofibromas
*mixed
*Papillomas
*Adenomas
*Chondromas
*Neuromas
*Fibroma/angiofibromas
*mixed
Generally:-
Malignant:
* ____________ carcinoma
* ____________
* ________carcinoma/Adenocystic Ca.
* ____________/____________/____________ Ca.
*Melanomas
* ________Cell Carcinoma
*Neuroblastoma
Malignant:
* Squamous cell carcinoma
*Lymphoma
*Adenocarcinoma/Adenocystic Ca. *Papillary/Medullary/Follicular Ca.
*Melanomas
*Basal Cell Carcinoma
*Neuroblastoma
Generally:-
Intermediate: *_____________
*Ameloblastoma
* Chemodectomas
Inverted papilloma
Manifestations of head and neck tumors
- Dependent on _____________
- _____________ enlargement
- _________ in affected areas
- Signs of _____________
Manifestations
- Dependent on the site affected
- Lymph node enlargement
- Pain in affected areas
- Signs of metastasis
Larynx
‘Voice box’
Males: female ratio : ____:___
Risk Factors –________,_______ , __________ lesion- laryngeal papilloma, previous ________, long standing __________
1-7:1
smoking , alcohol
pre- cancerous
irradiation; reflux laryngitis
Diagnosis of laryngeal tumors= hx, exam + inv
Hoarseness- _________ and ___________
Noisy/difficulty in breathing/________ . Airway obstruction
Aspiration
Video Laryngoscopy - Vocal/supraglottic lesion
CT/MRI – extent of tumour + nodal met. Biopsy carried out commonly under G.A
progressive and unremitting
stridor
Classification of laryngeal tumor - T N M
T1 – tumour is _____________, may involve ant. or post. Commissure with ___________
T2- Tumour extends to_______________ with impaired ___________
T3-Tumor limited to the _________ with __________
T4a- Tumor ________ the larynx.
T4b- encases _________, invades ____________
limited to the VC; normal mobility
supraglottic or subglottic; VC mobility
larynx with VC fixation
beyond
carotid; mediastinum
Nodal classification
N1- ____lateral node <___cm
N2a- ____lateral node >___ but </=___cm
N2b-multiple _____lat. Nodes ______ >6cm
N2c- ______lateral node/——lateral nodes none >6cm
N3- Any node>6cm
ipsi;3
ipsi;3;6
ipsi; none
contra;bi
Treatment of laryngeal tumor
Initial __________ for pt with airway obstruction.
Surgery – __________-total or partial, Partial- Vertical or Horizontal
Total- complete removal with a ____________________ , +/-speaking valve/voice prosthesis.
+/-Neck Dissection where there is nodal metastasis.
•___________
tracheostomy
Laryngectomy
permanent tracheostomy
Radiation
Prognosis in laryngeal tumors
In early stages nearly _____% 5year survival rate
Late stages _______% 5 year survival.
100
30-45
Nasopharyngeal tumour
Occur within the nasopharyngeal space Often from the __________________
Closely related to the ____________ and ____________ space
Anteriorly with the ____________
Superiorly -____________ (basi-sphenoid) Supero-laterally -____________
Inferiorly the -____________
fossa of Rossenmuller
eustachian tube ; parapharyngeal space
nasal cavity ; base of skull
orbit ; oropharynx
Nasopharyngeal tumors
epidemiology
Occurs 1/100,000 per population
Most prevalent among the _________ and and people of _________ descent,
Higher among the _________ within the subregion
Higher among _________/_________ americans
Chinese ; asian
North africans
chinese/asian americans