HEAD & NECK TUMOURS Flashcards

1
Q

Region described from the ___________ to the _________________.

  • excludes tumours of the ___________ contents and tumours of the ___________ and ___________
A

cranium ; base of the neck.

intracranial

globe and orbit

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2
Q

Head and neck tumors

Constitutes ____% of all cancers
Approx 500,000 cases diagnosed annually Approx. 300,000 deaths worldwide
Male : Female ___:____

A

3-5

2:1

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3
Q

Head and neck tumors Can be
- __________ , __________ or __________
- __________ and __________ tumours.

A

Can be
- benign, intermediate or malignant
- Epithelial and non-epithelial tumours.

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4
Q

Generally –
Benign:
*___________
* ___________
* ___________
* ___________
*Fibroma/angiofibromas
*mixed

A

*Papillomas
*Adenomas
*Chondromas
*Neuromas
*Fibroma/angiofibromas
*mixed

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5
Q

Generally:-

Malignant:
* ____________ carcinoma
* ____________
* ________carcinoma/Adenocystic Ca.
* ____________/____________/____________ Ca.
*Melanomas
* ________Cell Carcinoma
*Neuroblastoma

A

Malignant:
* Squamous cell carcinoma
*Lymphoma
*Adenocarcinoma/Adenocystic Ca. *Papillary/Medullary/Follicular Ca.
*Melanomas
*Basal Cell Carcinoma
*Neuroblastoma

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6
Q

Generally:-

Intermediate: *_____________
*Ameloblastoma
* Chemodectomas

A

Inverted papilloma

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7
Q

Manifestations of head and neck tumors
- Dependent on _____________
- _____________ enlargement
- _________ in affected areas
- Signs of _____________

A

Manifestations
- Dependent on the site affected
- Lymph node enlargement
- Pain in affected areas
- Signs of metastasis

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8
Q

Larynx
‘Voice box’

Males: female ratio : ____:___
Risk Factors –________,_______ , __________ lesion- laryngeal papilloma, previous ________, long standing __________

A

1-7:1

smoking , alcohol

pre- cancerous

irradiation; reflux laryngitis

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9
Q

Diagnosis of laryngeal tumors= hx, exam + inv

Hoarseness- _________ and ___________
Noisy/difficulty in breathing/________ . Airway obstruction
Aspiration
Video Laryngoscopy - Vocal/supraglottic lesion
CT/MRI – extent of tumour + nodal met. Biopsy carried out commonly under G.A

A

progressive and unremitting

stridor

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10
Q

Classification of laryngeal tumor - T N M
T1 – tumour is _____________, may involve ant. or post. Commissure with ___________
T2- Tumour extends to_______________ with impaired ___________
T3-Tumor limited to the _________ with __________
T4a- Tumor ________ the larynx.
T4b- encases _________, invades ____________

A

limited to the VC; normal mobility

supraglottic or subglottic; VC mobility

larynx with VC fixation

beyond

carotid; mediastinum

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11
Q

Nodal classification
N1- ____lateral node <___cm
N2a- ____lateral node >___ but </=___cm
N2b-multiple _____lat. Nodes ______ >6cm
N2c- ______lateral node/——lateral nodes none >6cm
N3- Any node>6cm

A

ipsi;3

ipsi;3;6

ipsi; none

contra;bi

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12
Q

Treatment of laryngeal tumor

Initial __________ for pt with airway obstruction.
Surgery – __________-total or partial, Partial- Vertical or Horizontal
Total- complete removal with a ____________________ , +/-speaking valve/voice prosthesis.
+/-Neck Dissection where there is nodal metastasis.
•___________

A

tracheostomy

Laryngectomy

permanent tracheostomy

Radiation

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13
Q

Prognosis in laryngeal tumors

In early stages nearly _____% 5year survival rate
Late stages _______% 5 year survival.

A

100

30-45

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14
Q

Nasopharyngeal tumour

Occur within the nasopharyngeal space Often from the __________________
Closely related to the ____________ and ____________ space
Anteriorly with the ____________
Superiorly -____________ (basi-sphenoid) Supero-laterally -____________
Inferiorly the -____________

A

fossa of Rossenmuller

eustachian tube ; parapharyngeal space

nasal cavity ; base of skull

orbit ; oropharynx

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15
Q

Nasopharyngeal tumors

epidemiology
Occurs 1/100,000 per population
Most prevalent among the _________ and and people of _________ descent,
Higher among the _________ within the subregion
Higher among _________/_________ americans

A

Chinese ; asian

North africans

chinese/asian americans

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16
Q

Risk Factors of nasopharyngeal tumors

_____ gender
Ingestion of ____________ meals and other nitrosamine containing diets
____________ of NPC
____________ infection
Genetic factors
Tobacco, Alcohol
Exposure to ____________

A

Male ; salted ungutted meals

Family hx ; Ebstein Barr Virus

wood dust

17
Q

Diagnosis of nasopharyngeal tumors- hx, exam
Nasal obstruction
__________
____________ hearing loss
Cervical lymphadenopathy
_________/_________/________
Nasoendoscopy &
Biopsy of nasopharyngeal mass for Histopathology

A

Epistaxis; Conductive

Proptosis; diolopia; headache

18
Q

Oropharyngeal tumor
Area bounded by
1. ________________ and the ____________
2. The ________ /________ fossae
3. Oropharyngeal surface of the soft palate and the oropharyngeal isthmus
4. Communicates inferiorly with the ________ and ________

A

Anterior faucial pillars ; base of the tongue

tonsil/tonsillar

larynx and hypopharynx

19
Q

Risks of Oropharynheal tumors

__________
Heavy _______ use
________ infection
Previous head and neck tumor
Previous _________ to the head and neck

A

Risks
Smoking
Heavy alcohol use
HPV 16 infection
Previous head and neck tumor
Previous radiation to the head and neck

20
Q

Sinonasal tumours
Tumours of the nose and paranasal sinuses
Constitutes <1% of all tumours
Late presentation/diagnosis due to non- specificity of early symptoms often taken for usual ‘_______’

A

catarrh