Head And Neck Pathology Flashcards

1
Q

Caused by focal demineralization of tooth structure by acidic metabolites of fermenting sugars that are produced by bacteria

A

Caries (tooth decay)

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2
Q

Main cause of tooth loss before age 35

A

Caries (tooth decay)

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3
Q

Inflammation of the oral mucosa surrounding the teeth

A

Gingivitis

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4
Q

It is the result of a poor oral hygiene and leads to the accumulation of dental plaque and calculus

A

Gingivitis

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5
Q

Is a sticky, colorless, biofilm that collects between and on the surface of the teeth

A

Dental plaque

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6
Q

Mixture of dental plaque is composed of?

A

Mixture of bacteria, salivary proteins, and desquamated epithelial cells

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7
Q

Is an inflammatory process that affects the supporting structure of the teeth (PDL) alveolar bone, and cementum

A

Periodontitis

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8
Q

Are common, often recurrent, exceedingly painful, superficial oral mucosal ulceration of unknown etiology

A

Aphthous ulcers (canker sores)

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9
Q

Irritation fibroma, also called traumatic fibroma an focal fibrous hyperplasia

Occurs primarily on the buccal mucosa along the bite line or the gingiva

A

Fibrous proliferative lesions

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10
Q

Where does fibrous proliferative lesion occurs

A

Buccal mucosa along the bite line or the gingiva

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11
Q

inflammatory lesion typically found on the gingiva of children, young adults, and pregnant women (pregnancy tumor)

A

Pyogenic granuloma

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12
Q

Common gingival growth that is most likely reactive in nature rather than neoplastic

A

Peripheral ossifying fibroma

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13
Q

Some of this condition may arise from a longstanding pyogenic granuloma, while others develop de novo from cells of the PDL

A

Peripheral ossifying fibroma

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14
Q

Uncommon lesion of the oral cavity, particularly the gingiva

Represent a reactive/inflammatory, rather than neoplastic process

A

Peripheral gian cell granuloma

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15
Q

Orofacial herpetic infection are caused by herpes simplex virus type 1 (HSV1 but oral HSV2 infection do occur

A

Herpes simplex virus infection

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16
Q

What causes herpes simplex virus infection

A

Caused by herpes simplex virus type 1 (HSV1)

But

Genital herpes do occur (HSV2)

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17
Q

Herpes simplex virus typically ovccur in ages between?

A

2 and 4, and are often asymptomatic

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18
Q

The most common fungal infection of the oral cavity

A

Oral candidiasis

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19
Q

The normal component of the oral flora

A

Candida albicans

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20
Q

Three major clinical forms of oral candiiasis

A
  1. Psuedomembranous (aka thruh)
  2. Erythematous
  3. Hyperplastic
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21
Q

Distinctive oral lesion on the lateral border of the tongue that is usually seen in immunocompromised patient and is caused by epstein-barr virus

A

Hairy leukoplakia

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22
Q

Microscopic feature of hairy leukoplakia

A

Hyperparakerasotis and acanthosis with “balloon cells” in the upper spinous layer

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23
Q

Precancerous and cancerous lesions

A

Leukoplakia
Erythroplakia
Squamous cell carcinoma

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24
Q

a white patch or plaque that cannot be scraped off and cannot be characterized clinically or pathologically as any other disease

A

Leukoplakia

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25
Red, velvety, possibly eroded area within the oral cavity that usually remains level with or may be slightly depressed in relation to the surrounding mucosa
Erythroplakia
26
Approx 95% of cancers of the head and neck are this disease
Squamous cell carcinoma
27
Is the pathogenesis of squamous cell carcinoma multifocal?
Yep
28
Approx how many % of squamous cell carcinoma in the oropharynx
70%
29
It is derived from remnants of odontogenic epithelium present within the jaws
Odontogenic cysts and tumors
30
Cyst that originates around the crown of an unerupted tooth and is thought to be the result of fluid accumulating between developing tooth and the dental follicle
Dentigerous cyst
31
A common cyst lesion found at the apex of teeth
Periapical cyst
32
Tumor that is common in male within the posterior mandible
Keratocystic odontogenic tumor
33
Most common type of odontogenic tumor; shows extensive deposition of enamel and dentin
Odontoma
34
An odontogenic tumor that has no ectomesenchymal differentiation
Amelobastoma
35
Often reffered as (common cold)
Infectious rhinitis
36
An IgE mediated immune reaction with an early and late phase response
Allergic rhinitis
37
Sequel to repeated attacks of acute rhinitis, either microbial or allergic in origin, with the eventual development of superimposed bacterial infection
Chronic rhinitis
38
Most commonly preceded by acute or chronic rhinitis, but maxillary sinusitis occasionally arises by extension of a periapical infection through the bony floor of the sinus
Sinusitis
39
Recurrent attacks of rhinitis may eventually lead to focal protrusion of the mucosa
Nasal polyps
40
Frequent features of viral upper respiratory infections
Pharyngitis and tonsilitis
41
Common microbe in pharyngitis and tonsilitis
B-hemolytic streptococci
42
Benign, highly vascular tumor that occur almost exclusively in adolescent males who are often fairskined and read headed
Nasopharyngeal angiofibroma
43
Benign neoplasm arising from the respiratory or schneiderian mucosa lining that nasal cavity and paranasal sinuses
Sinonasal (schneiderain) papilloma
44
Arise from the neuroectodermal olfactory cells present within th mucosa, particularly in the superior aspect of the nasal cavity
Olfactory neuroblastoma (esthesioneuroblastoma)
45
Uncommon tumor that may occur in the nasopharynx, the salivary gland, or in other midline structure in the thorax or abdomen
NUT midline carcinoma
46
Characterized by a distinctive geographic distribution, a close anatomic relationship to lymphoid tissue, and an associated with EBV infections
Nasopharyngeal carcinoma
47
Called polyps, sometimes develop on the vocal cords, most often in heavy smokers or in individual who impose great stain of their vocal cords (singer’s nodules)
Reactive nodules
48
Singers nodules are __ lesions And Polys are _ lesion
Bilateral Unilateral
49
Benign neoplasm, usually located on the true vocal cords, that form soft, raspberry-like proliferations rarely more than 1cm in diameter
Squamous papilloma and papillomatosis
50
Referred to as juvenile laryngeal papillomatosis
Papillomas
51
3 pathology in ears
Otitis media Cholesteatomas Otosclerosis
52
Occurs mainly in infants and children. It has both acute and chronic disease In acute it is caused by infections such as: streptococcus pneumonia Chronic infections: pseudomonasaeruginosa, staphylococcus aureus
Otitis media, acute or chronic
53
Associated with otitis media, are non-neoplastic cystic lesion 1 to 4 cm in diameter, lined by keratinizing squamous epithelium or metaplastic mucus-secreting epithelium, and filled with amorphus debris
Cholesteatomas
54
Abnormal bone depositio in te middle ear about the rim of the oval window into which the footplate of the stapes fits Associated with hearing loss, caused by the abnormal deposition of bone in the middle ear
Otosclerosis
55
2 neck lesions
Branchial cyst (cervical lymphoepithelial cyst) Thyroglossal duct cyst
56
Arise from remnant of the second branchial arch and are most commonly observed in young adults between the ages of 20 and 40
Branchial cyst
57
remnants of thyroid gland development may persist, producing cysts, 1 to 4 cm in diameter
Thyroglossal duct cyst
58
5 salivary glands diseases
S W A M P Sialadenitis Pleomorphic adenoma Warthin tumor Mucoepidermoid carcinoma Adenoid cystic carcinoma
59
Most common form of viral sialadenitis is?
Mumps
60
The most common type of inflammatory salivary gland lesion
Mucoceles
61
May be induced by trauma, viral or bacterial infetion or autoimmune disease in the salivary gland
Sialadenitis
62
A benign tumor that consists of a mixture of ductal and myoepithelial cells, they show both mesenchymal and epithelial differentiation
Pleomorphic adenoma
63
How many % of tumor in parotid in pleomorphic adenoma
60% parotid Less in submandibular Rare in minor salivary glands
64
Second most common salivary gland neoplasm More common in male Smokers are 8 times more at risk
Warthin tumor
65
Composed of squamous cell, mucus secreting cells and intermediate cells 15% of all salivary gland tumors, they occur mainly (60% to 70%) in the parotids
Mucoepidermoid carcinoma
66
Relatively incommon tumor tat approx 50% of cases is found in the minor salivary glands Th parotid and submandibular glands are most common
Adenoid cystic carcinoma
67
Examples of viruses in infectious rhinitis
Adenovirus Echoviruses Rhinoviruses
68
Viral reactivation of herpes simplex virus infection
Recurrent herpetic stomatitis
69
Pathogenesis of SCC
NA and EU: smoked tobacco and alcohol India and Asia: chewing of betel quid and paan Pipe smoking (lower lip)
70
particularly what type of HPV variant is involved in SCC in the oropharynx?
HPV-16
71
Favored locations of the SCC in oropharynx
Ventral surface of the tongue Floor of the mouth Lower lip Soft palate Gingiva
72
What histologic classification is dentigerous cyst?
Developmental cyst
73
What type of histologic classification is odontogenic keratocyst
Developmental cyst
74
What histologic classification is periapical cyst?
Inflammatory cyst
75
3 inflammatory of odontogenic cysts
Periapical cyst Residual cyst Paradental cyst
76
Give at least 3-4 developmental odontogenic cyst
(D O G G E) LGC Dentigerous cyst Odontogenic keratocyst Gingival cyst of newborn Gingival cyst of adult Eruption cyst Lateral periodontal cyst Glandular odontogenic cyst Calcifying epithelial odontogenic cyst
77
Most common form of sinonasal papilloma
Exophytic HPV 6 and 11
78
The only tumor virtually restricted to the parotid
Warthin tumor