Head And Neck Cancers Flashcards

1
Q

Head and neck cancers are typically what in origin?

A

Squamous cell in origin

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2
Q

Nasopharyngeal cancer is more commonly seen where in the world, 2 places?

A

Mediterranean and Far East.

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3
Q

What are the two most common risk factors for head and neck cancers?

A

Alcohol and smoking

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4
Q

What is a big time risk factor for oral cancers?

A

Smokeless tobacco

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5
Q

What are two other potential carcinogens for head and neck cancer?

A

Marijuana and occupational exposures.

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6
Q

What infection is frequently associated with nasopharyngeal cancer?

A

EBV

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7
Q

Besides EBV, what are two other associations with nasopharyngeal cancer?

A

Eating salted fish and in door pollution

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8
Q

What etiology are we thinking with oropharynx cancer?

A

HPV 16

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9
Q

What age of patient population are we dealing with in HPV related oropharyngeal cancer?

A

Younger patient population

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10
Q

Most tobacco related head and neck cancers occur in what age of patients? Which gender is more likely to get head and neck cancers?

A

60s

Male

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11
Q

What is an area of clinical presentation with nasopharynx cancers?

A

Obstruction of the ear canal, so ear pain

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12
Q

What is an early symptom of laryngeal carcinoma?

A

Hoarseness

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13
Q

What are two symptoms of advanced head and neck cancers he mentioned?

A

Weight loss and trismus

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14
Q

What tumor classification of head and neck represents invasion of an adjacent structure?

A

T4

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15
Q

How do we classify head and neck cancers for the intent of treatment?

A

Local or regionally advanced disease

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16
Q

How are we going to treat local cancers?

A

Surgery or radiation by curative intent

17
Q

What is the preferred therapy for laryngeal cancer?

A

Radiation

18
Q

What is the preferred therapy for oral cavity?

A

Surgery

19
Q

What do we mean when we say regionally advanced cancer?

A

We have a primary tumor and lymph node involvement

20
Q

What is the most common way to treat regionally advanced cancer?

A

Combo of chemo and radiation

21
Q

What is a approach we need to think about with regionally advanced and involving surgery?

A

We might be able to shrink the tumor down with chemo and radiation and then it be small enough to remove with surgery.

22
Q

What can lower the incidence of head and neck cancers?

A

Fruits and vegetables

23
Q

What has been shown to be protective against head and neck cancers?

A

Carotenoids and retinoids

24
Q

What does the term field cancerization mean?

A

Because of the structure and anatomy of the upper airways, carcinogens are essentially sprayed everywhere so lots of tissue can be exposed.

25
Q

What are two options for laryngectomized patients?

A

Electrolarynx and talking tracheostomy (synthetic vocal cords)