HDFN Flashcards

1
Q

other name for HDFN

A

erythroblastosis fetalis

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2
Q

neonatal testing

A

testing of newborn up to 28 days after delivery

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3
Q

perinatal testing

A

testing from 28 weeks of gestation to 28 days after delivery

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4
Q

HDFN can only occur if

A

red cell antibodies from the mother must be IgG
fetus contains an antigen that is absent from the mother
the antigen in the fetus is well developed

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5
Q

most common type of HDFN during the first pregnancy

A

ABO

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6
Q

most common HDFN during the second pregnancy

A

Rh ALSO THE MOST SEVERE TYPE OF HDFN

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7
Q

treatment for ABO HDFN

A

phototherapy

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8
Q

treatment for Rh HDFN

A

exchange transfusion

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9
Q

prenatal testing is done:

A

before delivery; FIRST TRIMESTER

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10
Q

purpose of prenatal/antepartum testing

A

to identify D-negative women who are candidates for RhIG

to identify women with antibodies capable of causing HDFN

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11
Q

ultrasound techniques

A

detect a fetal anemia

COLOR DOPPLER ULTRASONOGRAPHY

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12
Q

amniocentesis

A

change in optical density plotted on Liley graph from 27 to 40 weeks of gestation

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13
Q

if Rh- mother with Rh+ baby and negative rosette test

A

give 1 vial/dose of RhIG

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14
Q

who are not candidates for RHIG

A

mother with already active anti-D

Rh neg mother with Rh neg baby

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15
Q

candidates for RHIG

A

Rh neg mother with Rh pos baby and no antibodies formed from the previous pregnancy

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16
Q

cordocentesis

A

umbilical cord is punctured

measure H/H or biochemical bilirubin

17
Q

cord blood testing:

A

determined whether Rh neg mother should recieve postpartum RHIG

18
Q

intrauterine transfusion (in utero)

A
"O" negative 
RBC collected within 7 days
irradiated
CMV seronegative
Hb S neg

prevent potential HEART FAILURE

19
Q

exchange transfusion (post partum)

A
"O" negative IN AB PLASMA
RBC collected within 7 days
irradiated
CMV seronegative
Hb S neg

correct anemia, remove sensitized cells, reduce maternal Ab

20
Q

most frequently used method for screening FMH

A

rosette test

21
Q

1 dose RhIg contains

A

300 ug

22
Q

principle of Kleihauer-Betke test

A

acid elution

23
Q

measures fetal hemoglobin or Rh pos cell or both

A

flow cytometry