HC11- Clinical radiotherapy Flashcards
treatment cancer
surgery - radiotherapy - chemotherapy - immunotherapy
clinical factors radiotherapy (6)
- tumor size
- localization
- primary tumor
- metastases
- histology
- fitness patient
radiosensitivity > very sensitive
lymphoma, seminoma, small cell lung cancer
dosage very sensitive > microscopic
20-40 Gy
dosage very sensitive > macroscopic
30-60 Gy
radiosensitivity > average sensitivity
carcinoma
dosage average sensitivity > microscopic
40-60 Gy
dosage average sensitivity > macroscopic
60-80 Gy
radiosensitivity > not sensitive
sarcoma, glioblastoma, melanoma
dosage not sensitive > microscopic
60-80 Gy
dosage not sensitive > macroscopic
> 80 Gy
tissue sensitivity
- bone marrow
- hair
- brain
- lungs
- spinal cord
- kidneys
- small intestine
- skin
- bone marrow = 8 Gy
- hair = 10 Gy
- brain = 30-60 Gy
- lungs = 20-40 Gy
- spinal cord = 50-60 Gy
- kidneys = 15-20 Gy
- small intestine = 40-70 Gy
- skin = 70-80 Gy
challenge radiotherapy
killing the tumor without killing the patient
treatment recurring mammacarcinoma
hyperthermia and reirradiation
hyperthermia > WIRA
water-filtered infrared A > 434 MHz probe